Cytokine genes taking part in the immunological response to Helicobacter pylori infection
are good candidates to study for genetic predisposition to duodenal ulcer disease (DU) …

Besides environmental factors, the genetic background of an individual may contribute to the
development and final outcome of peptic ulcer disease. Interleukin-1 β (IL-1 β) and the …

Recent studies have reported the association of a pro‐inflammatory profile of genetic
polymorphisms in IL‐1B, IL‐1RN, TNF‐A, and IL‐10 genes with an increased risk of non …

Our aim was to investigate whether genetic polymorphism of IL‐1Β‐511, IL‐1RN, TNF‐A‐
308 are involved in the susceptibility to duodenal ulcer (DU). 437 unrelated Chinese Han …

Background. The host genetic factors that determine the clinical outcomes for Helicobacter
pylori‐infected individuals remain unclear. Aims. To elucidate the relations among …

It has been speculated that IL‐1 genes play a crucial role in the genetic predisposition to
duodenal ulcer upon H. pylori infection by modulating the host immune response. In the …

It remains controversial regarding the association between interleukin-8 (IL-8) gene− 251
T/A polymorphism and peptic ulcer disease (PUD) risk. Thus, a large-scale meta-analysis …

Background and aims. Helicobacter pylori infection almost invariably causes chronic
gastritis, but only a proportion of the infected subjects develop peptic ulcers. The local …

The purpose of this study was to assess the role of Helicobacter pylori and several genetic
polymorphisms in relation to inflammatory bowel disease (IBD). We studied 44 unrelated …

Results The seropositive rate of Helicobacter pylori (95/120 vs. 134/238, OR: 2.95, 95% CI
1.77-4.91), habitual smoking (67/120 vs. 82/238, OR: 2.40, 95% CI 1.54-3.77) and blood …