Alzheimer's disease (AD) is the primary cause of dementia. There is no effective treatment.
Amyloid-β peptide (Aβ) plays an important role in the pathogenesis and thus strategies …

Alzheimer's disease (AD) is a severe neurodegenerative disease for which there is currently
no effective treatment. This study investigated whether treatment with the herbal formula …

Background. Incipient Alzheimer's disease is often disguised as depressive disorder. Over
the course of AD, depressive symptoms are even more frequent. Hence, treatment with …

In the current study, we investigated the protective role of citalopram against cognitive
decline, impaired mitochondrial dynamics, defective mitochondrial biogenesis, defective …

A history of depression is a risk factor for Alzheimer's disease (AD), suggesting the
possibility that antidepressants administered prophylactically might retard the disease …

Tacrine (Amino tetrahydroacridine hydrochloride hydrate) is a non-competitive and
reversible inhibitor of acetylcholine esterase, and butylcholinesterase. Alzheimer's disease …

The prevalence of Alzheimer's disease (AD) is higher in females than in males, and causes
more severe cognitive, memory and behavioral impairments. Previously, in male transgenic …

Rationale The interest for acetylcholinesterase inhibitors in the treatment of Alzheimer's
disease has been greatly renewed owing to the discovery of a broad range of additional …

Serotonin signaling suppresses generation of amyloid-β (Aβ) in vitro and in animal models
of Alzheimer's disease (AD). We show that in an aged transgenic AD mouse model …

A double blind, placebo-controlled phase II study revealed that the antihistamine,
Dimebon®(dimebolin, latrepirdine) improved cognition in Alzheimer disease (AD) patients …