Bidirectional communication between neurons and vascular cells is important to the
maintenance of the central nervous system (CNS) milieu. Vascular endothelial growth factor …

Blood brain barrier (BBB) injury is an important factor affecting the prognosis of ischemic
stroke. Extensive research on BBB injury has revealed that blood vessels and neural …

Vascular endothelial growth factor (VEGF) is a potent angiogenic factor. Despite
upregulation of VEGF in the brain in Alzheimer's disease (AD), probably in response to …

Alzheimer's disease (AD) is accompanied by the progressive deposition of β-amyloid (Aβ) in
both senile plaques and cerebral blood vessels, loss of central neurons, and vessel …

Brain function critically relies on blood vessels to supply oxygen and nutrients, to establish a
barrier for neurotoxic substances, and to clear waste products. The archetypal vascular …

Vascular endothelial growth factor (VEGF) has been shown to induce angiogenesis when
infused continuously into adult rat brain tissue. In addition, VEGF has been shown to …

Background Increasing evidence suggests that cerebral vascular dysfunction is associated
with the early stages of Alzheimer's disease (AD). Vascular endothelial growth factor (VEGF) …

Fifteen Alzheimer (AD) and fifteen normative (NM) age-matched autopsy brains were
analyzed in superior temporal cortex, hippocampal and brainstem samples. Vascular …

Vascular endothelial growth factor (VEGF) is an angiogenic growth factor that also induces
vascular permeability and macrophage migration. VEGF expression is weak in normal adult …

A large literature demonstrates the multifunctional nature of vascular endothelial growth
factor (VEGF). Though initially characterized as an endothelial cell-specific factor, recent …