The search for genetic determinants of human neural tube def... : Current Opinion in
Pediatrics The search for genetic determinants of human neural tube defects : Current …

Birth defects (congenital anomalies) are the leading cause of death in babies under 1 year
of age. Neural tube defects (NTD), with a birth incidence of approximately 1/1000 in …

It has been estimated that 60–70% of neural tube defects (NTDs) have a genetic component,
but few causative genes have been identified. The lack of information on genes associated …

The formation of the embryonic brain and spinal cord begins as the neural plate bends to
form the neural folds, which meet and adhere to close the neural tube. The neural ectoderm …

Congenital defects of neural tube closure (neural tube defects; NTDs) are among the
commonest and most severe disorders of the fetus and newborn. Disturbance of any of the …

Neural tube closure (NTC) is crucial for proper development of the brain and spinal cord and
requires precise morphogenesis from a sheet of cells to an intact three‐dimensional …

Neural tube defects (NTDs) represent a common group of severe congenital malformations
of the central nervous system. They result from failure of neural tube closure during early …

Neural tube defects (NTDs), including both spina bifida and anencephaly, are common
human congenital malformations that appear to be etiologically heterogeneous (Holmes et …

Neural tube defects (NTDs) are a group of severe congenital abnormalities resulting from
the failure of neurulation. The pattern of inheritance of these complex defects is …

Neural tube defects (NTDs) represent a common group of severe congenital malformations
that result from failure of neural tube closure during early development. Their etiology is …