Novel long‐acting bronchodilators for COPD and asthma

M Cazzola, MG Matera - British journal of pharmacology, 2008 - Wiley Online Library
An important step in simplifying asthma and chronic obstructive pulmonary disease (COPD)
management and improving adherence with prescribed therapy is to reduce the dose …

Pharmacology and therapeutics of bronchodilators

M Cazzola, CP Page, L Calzetta, MG Matera - Pharmacological Reviews, 2012 - ASPET
Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …

Ultra long-acting β2-agonists in development for asthma and chronic obstructive pulmonary disease

M Cazzola, MG Matera, J Lötvall - Expert opinion on investigational …, 2005 - Taylor & Francis
After the discovery of formoterol and salmeterol, new candidates for long-acting β2-
adrenoceptor agonists (LABAs) have emerged from various companies. In particular, once …

β2‐adrenoceptor agonists: current and future direction

M Cazzola, L Calzetta… - British journal of …, 2011 - Wiley Online Library
Despite the passionate debate over the use of β2‐adrenoceptor agonists in the treatment of
airway disorders, these agents are still central in the symptomatic management of asthma …

Pharmacology and therapeutics of bronchodilators revisited

MG Matera, CP Page, L Calzetta, P Rogliani… - Pharmacological …, 2020 - ASPET
Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma
and chronic obstructive pulmonary disease (COPD). There is therefore considerable interest …

Novel bronchodilators in asthma

M Cazzola, A Segreti, MG Matera - Current opinion in pulmonary …, 2010 - journals.lww.com
Bronchodilators are central in the symptomatic management of asthma. It is likely that the
once-daily dosing of a bronchodilator would be a significant convenience and probably a …

Ultra-Long-Acting β2-Adrenoceptor Agonists: An Emerging Therapeutic Option for Asthma and COPD?

MG Matera, M Cazzola - Drugs, 2007 - Springer
There has been a real interest recently in developing once-daily β2-adrenoceptor agonists
(ultra-long-acting β 2-adrenoceptor agonists [ultra-LABAs]) for treating asthma and chronic …

Muscarinic antagonist-β-adrenergic agonist dual pharmacology molecules as bronchodilators: a patent review

NC Ray, L Alcaraz - Expert Opinion on Therapeutic Patents, 2009 - Taylor & Francis
Background: The proven efficacy of several anti-cholinergics and β2-agonists and their
combinations in both chronic obstructive pulmonary disease (COPD) and asthma strongly …

Emerging inhaled bronchodilators: an update

M Cazzola, MG Matera - European Respiratory Journal, 2009 - Eur Respiratory Soc
Bronchodilators remain central to the symptomatic management of chronic obstructive
pulmonary disease and asthma, and, for this reason and also because the patent protection …

Bronchodilating drugs for chronic obstructive pulmonary disease: current status and future trends

P Montuschi, G Ciabattoni - Journal of medicinal chemistry, 2015 - ACS Publications
Inhaled bronchodilators, including long-acting muscarinic receptor antagonists (LAMA) and
long-acting β2-adrenoreceptor agonists (LABA), are the mainstay of pharmacological …