[HTML][HTML] Hybridization facilitates adaptive evolution in two major fungal pathogens

H Samarasinghe, M You, TS Jenkinson, J Xu… - Genes, 2020 - mdpi.com
Hybridization is increasingly recognized as an important force impacting adaptation and
evolution in many lineages of fungi. During hybridization, divergent genomes and alleles are …

[HTML][HTML] Chromosomal copy number variation, selection and uneven rates of recombination reveal cryptic genome diversity linked to pathogenicity

RA Farrer, DA Henk, TWJ Garner, F Balloux… - PLoS …, 2013 - journals.plos.org
Pathogenic fungi constitute a growing threat to both plant and animal species on a global
scale. Despite a clonal mode of reproduction dominating the population genetic structure of …

Genomic Correlates of Virulence Attenuation in the Deadly Amphibian Chytrid Fungus, Batrachochytrium dendrobatidis

JM Refsnider, TJ Poorten… - G3: Genes …, 2015 - academic.oup.com
Emerging infectious diseasespose a significant threat to global health, but predicting
disease outcomes for particular species can be complicated when pathogen virulence …

Coevolution of a generalist pathogen with many hosts: the case of the amphibian chytrid Batrachochytrium dendrobatidis

T Carvalho, AM Belasen, LF Toledo… - Current Opinion in …, 2024 - Elsevier
Generalist pathogens maintain infectivity in numerous hosts; how this broad ecological
niche impacts host–pathogen coevolution remains to be widely explored. Batrachochytrium …

Genomic studies of disease-outcome in host–pathogen dynamics

AV Longo, PA Burrowes, KR Zamudio - American Zoologist, 2014 - academic.oup.com
Pathogens act as agents of evolutionary change in host populations, altering the host's
allele frequencies and phenotypes through selection. The mechanisms underlying these …

First in Vivo Batrachochytrium dendrobatidis Transcriptomes Reveal Mechanisms of Host Exploitation, Host-Specific Gene Expression, and Expressed Genotype …

AR Ellison, GV DiRenzo, CA McDonald… - G3: Genes …, 2017 - academic.oup.com
For generalist pathogens, host species represent distinct selective environments, providing
unique challenges for resource acquisition and defense from host immunity, potentially …

Interspecific hybridization as a driver of fungal evolution and adaptation

J Steensels, B Gallone, KJ Verstrepen - Nature Reviews Microbiology, 2021 - nature.com
Cross-species gene transfer is often associated with bacteria, which have evolved several
mechanisms that facilitate horizontal DNA exchange. However, the increased availability of …

Globally invasive genotypes of the amphibian chytrid outcompete an enzootic lineage in coinfections

TS Jenkinson, D Rodriguez… - … of the Royal …, 2018 - royalsocietypublishing.org
Competition between genotypes is likely to be a key driver of pathogen evolution,
particularly following a geographical invasion by distant strains. Theory predicts that …

[HTML][HTML] Coinfection with chytrid genotypes drives divergent infection dynamics reflecting regional distribution patterns

T Carvalho, D Medina, L P. Ribeiro… - Communications …, 2023 - nature.com
By altering the abundance, diversity, and distribution of species—and their pathogens—
globalization may inadvertently select for more virulent pathogens. In Brazil's Atlantic Forest …

Amphibian-killing fungus loses genetic diversity as it spreads across the New World

G Velo-Antón, D Rodríguez, AE Savage… - Biological …, 2012 - Elsevier
Emergent infectious diseases are a severe threat to global biodiversity, thus conservation
biologists need to understand the emergence, spread, and evolution of pathogens to identify …