Alpha-glucosidase inhibition and molecular docking studies of 1, 2-benzothiazine 1, 1-dioxide based carbohydrazides.
Diabetes mellitus is a chronic disease in which the infected cells do not have the ability to
produce sufficient amount of insulin that results in the abnormality of carbohydrates …
produce sufficient amount of insulin that results in the abnormality of carbohydrates …
Synthesis of 1,2,3-benzotriazin-4(3H)-one derivatives as α-glucosidase inhibitor and their in-silico study
Abstract α-Glucosidase inhibition is considered as an effective strategy for the treatment of
diabetes mellitus. Currently, three α-glucosidase inhibitors are being used as drugs; …
diabetes mellitus. Currently, three α-glucosidase inhibitors are being used as drugs; …
Synthesis, biological evaluation and molecular docking study of benzimidazole derivatives as α-glucosidase inhibitors and anti-diabetes candidates
Voglibose and acarbose are distinguished α-glucosidase inhibitors used for controlling
diabetes mellitus. Unfortunately, these distinguished and clinically used inhibitors have also …
diabetes mellitus. Unfortunately, these distinguished and clinically used inhibitors have also …
[HTML][HTML] Exploring the therapeutic potential of benzothiazine-pyrazole hybrid molecules against alpha-glucosidase: Pharmacological and molecular modelling based …
S Taj, M Ahmad, A Alshammari, A Alghamdi… - Saudi Journal of …, 2022 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder and a significant health problem all over the
world. The current study elucidates the inhibitory potentials of the benzothiazine-pyrazole …
world. The current study elucidates the inhibitory potentials of the benzothiazine-pyrazole …
Alpha-glucosidase activity of novel pyrazolobenzothiazine 5, 5-dioxide derivatives for the treatment of diabetes mellitus. Invitro combined with molecular docking …
Diabetes mellitus is a metabolic disease caused due to the improper secretion of insulin
which leads to hyperglycaemia. According to the International Diabetes Federation (IDF) …
which leads to hyperglycaemia. According to the International Diabetes Federation (IDF) …
A Combined Experimental and Computational Study of Novel Benzotriazinone Carboxamides as Alpha-Glucosidase Inhibitors
Z Khalid, SS Shafqat, HA Ahmad, MA Munawar… - Molecules, 2023 - mdpi.com
Diabetes is a chronic metabolic disorder of the endocrine system characterized by persistent
hyperglycemia appears due to the deficiency or ineffective use of insulin. The glucose level …
hyperglycemia appears due to the deficiency or ineffective use of insulin. The glucose level …
Synthesis of novel substituted quinoline derivatives as diabetics II inhibitors and along with their in-silico studies
In this article, 26 compounds of substituted quinoline derivatives were synthesized and their
α-glucosidase inhibition activity against the α-glucosidase enzyme was investigated. The …
α-glucosidase inhibition activity against the α-glucosidase enzyme was investigated. The …
Synthesis, molecular docking study of thiazole derivatives and exploring their dual inhibitor potentials against α-amylase and α-glucosidase
Diabetes mellitus is one of the most chronic metabolic diseases. The current study
comprises of evaluation of thiazole as an antidiabetic agent. A library of sixteen derivatives …
comprises of evaluation of thiazole as an antidiabetic agent. A library of sixteen derivatives …
Synthesis of quinoline derivatives as diabetic II inhibitors and molecular docking studies
In searchof the potenttherapeutic agent as an α-glucosidase inhibitor, we have synthesized
twenty-five analogs (1–25) of quinoline-based Schiff bases as an inhibitoragainst α …
twenty-five analogs (1–25) of quinoline-based Schiff bases as an inhibitoragainst α …
[HTML][HTML] In-silico studies of some oxadiazoles derivatives as anti-diabetic compounds
An in-silico study was performed to investigate the anti-diabetic activities of 27 Oxadiazoles
derivatives. The anti-diabetic compounds were optimized using Density Functional Theory …
derivatives. The anti-diabetic compounds were optimized using Density Functional Theory …