Th-17 cytokines have been associated with the pathogenesis and development of several
autoimmune diseases. Th-17-induced inflammation affects the expression and transport …

Th-17 cytokines have been associated with the pathogenesis and development of several
autoimmune diseases. Th-17-induced inflammation affects the expression and transport …

Activated T helper 17 (Th-17) cytokines play a role in the pathophysiology of autoimmune
and infectious diseases. While these diseases affect many women of childbearing age, little …

Pronounced inflammation or infection associated changes in the expression of many key
placental transporters has been observed in human and rodent disease models, which are …

Background Several efflux and uptake transporters in the placenta are involved in the
transmembrane transport of endogenous substrates and xenobiotics. Their expression and …

The placenta is essential for regulating the exchange of solutes between the maternal and
fetal circulations. As a result, the placenta offers support and protection to the developing …

The placenta is essential for regulating the exchange of solutes between the maternal and
fetal circulations. As a result, the placenta offers support and protection to the developing …

Inflammation impacts the expression and function of drug transporters at term-gestation;
however, the impact of inflammation on the expression of drug transporters at mid-gestation …

Fetal drug exposure is determined by the type and concentration of placental transporters,
and their regulation is central to the development of new treatments and delivery strategies …

Inflammation accompany pregnancy for physiological reasons but can be also involved in
pathological process with deleterious effect on placental function and fetal development …