Opioid rotation is increasingly becoming an option to improve pain management especially
in long‐term treatment. Because of insufficient analgesia and intolerable side effects, a total …

Importance Individuals with chronic pain who use long-term opioid therapy (LTOT) are at risk
of opioid use disorder and other harmful outcomes. Rotation to buprenorphine may be …

Buprenorphine is an opioid, used in the United States and abroad for both analgesia and
addiction, with unique opioid receptor binding properties. There are several …

BACKGROUND:: Buprenorphine, a potent opioid analgesic, has been available in
parenteral and oral or sublingual (SL) formulations for> 25 years. In 2001, the …

Background: Sublingual buprenorphine-naloxone (buprenorphine SL) is a preparation that
is used to treat opioid dependence. In addition, the Drug Enforcement Administration (DEA) …

Aims: Opioids produce analgesia via different pain pathways. The aim of these case studies
was to address the issue of opioid rotation or switching, raising the important issue of …

This randomised, double-blind, placebo-controlled study evaluated the efficacy and
tolerability of buprenorphine TDS, a new transdermal formulation of the opioid analgesic …

The transdermal matrix patch formulation of buprenorphine has been shown to be effective
in managing moderate-to-severe cancer pain and severe pain unresponsive to nonopioid …

Abstract▴ Buprenorphine is a low molecular weight, lipophilic, opioid analgesic. Recently, a
transdermal matrix patch formulation of buprenorphine has become available in three …

IMPLICATIONS: These are the first case reports from clinical practice demonstrating the
successful use of the new transdermal formulation of buprenorphine for the treatment of …