Traits related to energy balance and obesity are exceptionally complex, with varying
contributions of genetic susceptibility and interacting environmental factors. The use of …

Multiple biological, behavioural and genetic determinants or correlates of obesity have been
identified to date. Genome-wide association studies (GWAS) have contributed to the …

Obesity is a major public health concern. This condition results from a constant and complex
interplay between predisposing genes and environmental stimuli. Current attempts to …

Obesity has reached epidemic proportions and is recognised as a significant global health
problem. Increased food intake and decreased physical activity are traditionally to blame for …

Candidate gene and genome-wide association studies have led to the discovery of nine loci
involved in Mendelian forms of obesity and 58 loci contributing to polygenic obesity. These …

Obesity is a complex and multifactorial disease that occurs as a result of the interaction
between “obesogenic” environmental factors and genetic components. Although the genetic …

Obesity is a classical complex trait, influenced by both genetic and lifestyle factors. The
number of obesity gene variants is currently unknown but, based on sound evolutionary …

It has long been known that there is a genetic component to obesity, and that characterizing
this underlying factor would likely offer the possibility of better intervention in the future …

Although genes causing rare Mendelian forms of human obesity have provided much useful
information about underlying causes of obesity, these genes do not explain significant …

This book comprehensively accounts the current understanding of genetic mechanisms of
obesity by analyzing obesity phenotypes and genotypes and, gene polymorphisms and …