Cerebral Diffusion and T2: MRI Predictors of Acute Mountain Sickness during Sustained High-Altitude Hypoxia

JS Hunt Jr, RJ Theilmann, ZM Smith… - Journal of Cerebral …, 2013 - journals.sagepub.com
Diffusion magnetic resonance imaging (MRI) provides a sensitive indicator of cerebral
hypoxia. We investigated if apparent diffusion coefficient (ADC) and transverse relaxation …

Magnetic resonance imaging evidence of cytotoxic cerebral edema in acute mountain sickness

K Kallenberg, DM Bailey, S Christ… - Journal of Cerebral …, 2007 - journals.sagepub.com
The present study applied T2-and diffusion-weighted magnetic resonance imaging to
examine if mild cerebral edema and subsequent brain swelling are implicated in the …

Hypoxia-induced acute mountain sickness is associated with intracellular cerebral edema: a 3 T magnetic resonance imaging study

GG Schoonman, PS Sándor… - Journal of Cerebral …, 2008 - journals.sagepub.com
Acute mountain sickness is common among not acclimatized persons ascending to high
altitude; the underlying mechanism is unknown, but may be related to cerebral edema. Nine …

Sustained high-altitude hypoxia increases cerebral oxygen metabolism

ZM Smith, E Krizay, J Guo, DD Shin… - Journal of Applied …, 2013 - journals.physiology.org
Acute mountain sickness (AMS) is a common condition occurring within hours of rapid
exposure to high altitude. Despite its frequent occurrence, the pathophysiological …

Regional cerebral blood flow during acute hypoxia in individuals susceptible to acute mountain sickness

EAW Dyer, SR Hopkins, JE Perthen, RB Buxton… - Respiratory physiology …, 2008 - Elsevier
Individuals susceptible to high altitude pulmonary edema show altered pulmonary vascular
responses within minutes of exposure to hypoxia. We hypothesized that a similar acute …

Early brain swelling in acute hypoxia

DJ Dubowitz, EAW Dyer… - Journal of Applied …, 2009 - journals.physiology.org
Acute mountain sickness (AMS) and high-altitude cerebral edema share common clinical
characteristics, suggesting cerebral swelling may be an important factor in the …

[HTML][HTML] MRI evidence: acute mountain sickness is not associated with cerebral edema formation during simulated high altitude

K Mairer, M Göbel, M Defrancesco, M Wille, H Messner… - PloS one, 2012 - journals.plos.org
Acute mountain sickness (AMS) is a common condition among non-acclimatized individuals
ascending to high altitude. However, the underlying mechanisms causing the symptoms of …

[HTML][HTML] Multiparametric magnetic resonance investigation of brain adaptations to 6 days at 4350 m

S Verges, T Rupp, M Villien, L Lamalle… - Frontiers in …, 2016 - frontiersin.org
Objective: Hypoxic exposure in healthy subjects can induce acute mountain sickness
including headache, lethargy, cerebral dysfunction, and substantial cerebral structural …

Cerebral volumetric changes induced by prolonged hypoxic exposure and whole-body exercise

T Rupp, M Jubeau, L Lamalle… - Journal of Cerebral …, 2014 - journals.sagepub.com
The present study assessed the isolated and synergetic effects of hypoxic exposure and
prolonged exercise on cerebral volume and subedema and symptoms of acute mountain …

Magnetic resonance investigation into the mechanisms involved in the development of high-altitude cerebral edema

RS Sagoo, CE Hutchinson, A Wright… - Journal of Cerebral …, 2017 - journals.sagepub.com
Rapid ascent to high altitude commonly results in acute mountain sickness, and on occasion
potentially fatal high-altitude cerebral edema. The exact pathophysiological mechanisms …