[HTML][HTML] ROCK2 Deficiency in Bone Marrow-Derived Cells Leads to Increased Cholesterol Efflux and Decreased Atherosclerosis
Q Zhou, Y Mei, T Shoji, X Han, K Kaminski, G Taeg… - Circulation, 2012 - ncbi.nlm.nih.gov
Background Macrophages play a central role in the development of atherosclerosis.
However, the signaling pathways that regulate their function are not well understood. The …
However, the signaling pathways that regulate their function are not well understood. The …
Rho-Associated Coiled-Coil-Containing Kinase 2 Deficiency in Bone Marrow–Derived Cells Leads to Increased Cholesterol Efflux and Decreased Atherosclerosis
Q Zhou, Y Mei, T Shoji, X Han, K Kaminski, GT Oh… - Circulation, 2012 - Am Heart Assoc
Background—Macrophages play a central role in the development of atherosclerosis.
However, the signaling pathways that regulate their function are not well understood. The …
However, the signaling pathways that regulate their function are not well understood. The …
critical role of ROCK2 in bone marrow-derived macrophages in mediating atherosclerosis
Q Zhou, JK Liao - 2010 - Am Heart Assoc
Background: Rho kinases (ROCKs) are serine-threonine protein kinases that are involved in
the regulation of the actin cytoskeleton. Recent studies suggest that ROCKs also play a …
the regulation of the actin cytoskeleton. Recent studies suggest that ROCKs also play a …
Deficiency of ROCK1 in macrophages protects against atherosclerosis
HW Wang, N Oyama, Y Rikitake, S Kitamoto, J Gitlin… - 2007 - Am Heart Assoc
Background: Rho kinases (ROCKs) are serine-threonine protein kinases that regulate
various cellular functions. There is increasing evidence that the RhoA/ROCK pathway plays …
various cellular functions. There is increasing evidence that the RhoA/ROCK pathway plays …
[HTML][HTML] Deficiency of ROCK1 in bone marrow-derived cells protects against atherosclerosis in LDLR−/− mice
HW Wang, PY Liu, N Oyama, Y Rikitake… - The FASEB …, 2008 - ncbi.nlm.nih.gov
Rho kinases (ROCKs) are serine-threonine protein kinases that regulate the actin
cytoskeleton. Recent studies suggest that ROCKs also play an important role in …
cytoskeleton. Recent studies suggest that ROCKs also play an important role in …
[HTML][HTML] ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury
K Noma, Y Rikitake, N Oyama, G Yan… - The Journal of …, 2008 - Am Soc Clin Investig
Although Rho-associated kinase (ROCK) activity has been implicated in cardiovascular
diseases, the tissue-and isoform-specific roles of ROCKs in the vascular response to injury …
diseases, the tissue-and isoform-specific roles of ROCKs in the vascular response to injury …
6-OR: Vascular Endothelial ROCK2 Deficiency Promotes Browning and Burning of White Adipose Tissue
Y Takeda, K Matoba, R Ukichi, K Sekiguchi, Y Nagai… - Diabetes, 2022 - Am Diabetes Assoc
The accumulation of visceral fat is associated with multiple coronary risk factors such as
glucose intolerance, dyslipidemia, and hypertension. We have previously demonstrated that …
glucose intolerance, dyslipidemia, and hypertension. We have previously demonstrated that …
ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells.
竹田裕介 - International journal of molecular sciences, 2021 - ir.jikei.ac.jp
The small GTPase Rho and its downstream effector, Rho-kinase (ROCK), regulate various
cellular functions, including organization of the actin cytoskeleton, cell adhesion and …
cellular functions, including organization of the actin cytoskeleton, cell adhesion and …
ROCK2 mediates the uptake of fatty acids through the transcriptional regulation of CD36
Background: Basal metabolic rate has a profound effect on the development of obesity and
protects against cold intolerance in living organisms. Rho-activated kinase 2 (ROCK2), an …
protects against cold intolerance in living organisms. Rho-activated kinase 2 (ROCK2), an …
[HTML][HTML] ROCK2 regulates monocyte migration and cell to cell adhesion in vascular endothelial cells
Y Takeda, K Matoba, D Kawanami, Y Nagai… - International journal of …, 2019 - mdpi.com
The small GTPase Rho and its downstream effector, Rho-kinase (ROCK), regulate various
cellular functions, including organization of the actin cytoskeleton, cell adhesion and …
cellular functions, including organization of the actin cytoskeleton, cell adhesion and …