Acute myocardial infarction and chronic heart failure rank among the major causes of
morbidity and mortality worldwide. Except for heart transplantation, current therapy options …

Stem cell therapy is a promising strategy for tissue regeneration. The therapeutic benefits of
cell therapy are mediated by both direct and indirect mechanisms. However, the application …

Stem cell therapy aimed at restoring organ function, notably myocardial repair and
regeneration postmyocardial infarction (MI), is one of the most exciting and promising …

The global impetus to identify curative therapies has been fuelled by the unmet needs of
patients in the context of a growing heart failure pandemic. To date, regeneration trials in …

Ischemic heart diseases (IHDs) remain major public health problems with high rates of
morbidity and mortality worldwide. Despite significant advances, current therapeutic …

Heart failure is the number one killer worldwide with~ 50% of patients dying within 5 years of
prognosis. The discovery of stem cells, which are capable of repairing the damaged portion …

Given the rising prevalence of cardiovascular disease worldwide and the limited therapeutic
options for severe heart failure, novel technologies that harness the regenerative capacity of …

Stem cell therapy is a promising approach to the treatment of ischemic heart disease via
replenishing cell loss after myocardial infarction. Both preclinical studies and clinical trials …

As part of the TACTICS (Transnational Alliance for Regenerative Therapies in
Cardiovascular Syndromes) series to enhance regenerative medicine, here, we discuss the …

Cell therapy has the potential to improve healing of ischemic heart, repopulate injured
myocardium and restore cardiac function. The tremendous hope and potential of stem cell …