Cyclooxygenase (COX) is a key enzyme responsible for inflammation, converting
arachidonic acid to prostaglandin and thromboxane. COX has at least two isoforms, COX-1 …

Objective. The purpose of this study is to describe the expression of cyclooxygenase (COX)
2 cervical intraepithelial neoplasia (CIN) and vulvar cancer specimens. Materials and …

BACKGROUND.: Recent studies have demonstrated that cyclooxygenase-2 (COX-2)
expression is up-regulated in a number of cancers. Selective inhibition of COX-2 offers a …

Multiple lines of evidence suggest that cyclooxygenase-2 (COX-2) is an important target for
preventing epithelial malignancies. Little is known, however, about the expression of COX-2 …

OBJECTIVE: Previous data demonstrate an association between cyclooxygenase activity
and development of cervical cancer. This review investigates the role of cyclooxygenase-2 …

Many pathological conditions including most cancers show an exacerbated activation of the
inflammatory pathways and their sustained maintenance. In cervical carcinogenesis, the …

Carcinogenesis results from the long-term accumulation of genetic and epigenetic
aberrations at the molecular level, which are under constant selection pressure for growth …

Abstract Inhibition of cyclooxygenase-2 (COX-2) pathways may have significant implications
for the prevention and treatment of head and neck squamous cell carcinoma (HNSCC). COX …

This study was designed to investigate the expression and molecular signaling of
cyclooxygenase-1 (COX-1) in cervical carcinomas. Real-time quantitative reverse …

The existing epidemiologic literature was comprehensively reviewed to retrieve all
epidemiologic studies (case control and cohort studies) that examined exposure to …