The kinetic properties of wild-type rat brain IIa sodium channels in excised macropatches
were studied using step depolarizations and ramp depolarizations to imitate the slow settling …

Sodium currents, I Na, were recorded from Xenopus laevis oocytes which had been injected
with mRNA synthesized by in vitro transcription of the rat brain sodium channel II cDNA …

Chick neuronal Na+ channels were expressed in Xenopus laevis oocytes after injection with
total messenger ribonucleic acid (mRNA) isolated from chick brain. The currents were …

Na currents recorded from inside-out macropatches excised from Xenopus oocytes
expressing the α subunit of the rat brain Na channel IIA show at least two distinguishable …

Rat brain IIA sodium channel α-subunits were expressed in Xenopus oocytes, and the
sodium currents were measured by intracellular voltage clamping with large agarose-tipped …

The two electrode voltage clamp technique was used to study voltage-dependent sodium
currents (INa) in Xenopus laevis oocytes previously injected with mRNA extracted from adult …

Several cloned sodium channels were expressed in oocytes and compared with respect to
their sensitivity to internal Mg 2+ concerning the open-channel block and to external Ca 2+ …

Whole-cell gating current recording from rat brain IIA sodium channels in Xenopus oocytes
was achieved using a high-expression system and a newly developed high-speed two …

Abstract Short (< 1 sec) duration depolarization of Xenopus laevis oocytes to voltages
greater than+ 40 mV activates a sodium-selective channel (Nax) with sodium permeability …

Voltage-gated sodium channels in the mammalian CNS initiate and propagate action
potentials when excitatory inputs achieve threshold membrane depolarization. There are …