Effects of long-term monotherapy with enalapril, metoprolol, and digoxin on the progression of left ventricular dysfunction and dilation in dogs with reduced ejection …

HN Sabbah, H Shimoyama, T Kono, RC Gupta… - Circulation, 1994 - Am Heart Assoc
BACKGROUND Recent clinical trials have suggested that therapy with angiotensin-
converting enzyme inhibitors in asymptomatic patients with reduced left ventricular (LV) …

Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dilatation in patients with asymptomatic systolic …

MA Konstam, MW Kronenberg, MF Rousseau… - Circulation, 1993 - Am Heart Assoc
BACKGROUND Patients with heart failure and reduced left ventricular (LV) ejection fraction
(EF) manifest progressive LV dilatation, which is prevented by angiotensin converting …

Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dysfunction in patients with heart failure. SOLVD …

MA Konstam, MF Rousseau, MW Kronenberg… - Circulation, 1992 - Am Heart Assoc
BACKGROUND In patients with heart failure, activation of the renin-angiotensin system is
common and has been postulated to provide a stimulus for further left ventricular (LV) …

Angiotensin converting enzyme inhibition and ventricular remodeling in heart failure

JM Pfeffer, MA Pfeffer - The American journal of medicine, 1988 - Elsevier
The prevention or attenuation of the development of heart failure by the angiotensin
converting enzyme inhibitor captopril was examined in two animal models, spontaneously …

Effects of long-term enalapril therapy on left ventricular diastolic properties in patients with depressed ejection fraction. SOLVD Investigators.

H Pouleur, MF Rousseau, C van Eyll, L Stoleru… - Circulation, 1993 - Am Heart Assoc
BACKGROUND The aim of the present study was to analyze the changes in left ventricular
diastolic function that occur in patients with chronic severe left ventricular systolic …

[HTML][HTML] Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions

SOLVD Investigators* - New England Journal of Medicine, 1992 - Mass Medical Soc
Background. It is not known whether the treatment of patients with asymptomatic left
ventricular dysfunction reduces mortality and morbidity. We studied the effect of an …

Long-term captopril treatment improves diastolic filling more than systolic performance in rats with large myocardial infarction

SE Litwin, SE Katz, JP Morgan, PS Douglas - Journal of the American …, 1996 - Elsevier
Objectives. This study sought determine the effects of long-term angiotensin-converting
enzyme (ACE) inhibition on left ventricular (LV) diastolic filling in postinfarction heart failure …

Increased survival in rats with congestive heart failure treated with enalapril

CS Sweet, SE Emmert, II Stabilito… - Journal of …, 1987 - journals.lww.com
Vasodilating drugs such as angiotensin converting enzyme (ACE) inhibitors may extend life
expectancy in patients with congestive heart failure (CHF). The purpose of this study was to …

Angiotensin-converting enzyme inhibition and beta-adrenoceptor blockade regress established ventricular remodeling in a canine model of discrete myocardial …

KM McDonald, T Rector, PF Carlyle, GS Francis… - Journal of the American …, 1994 - Elsevier
Objectives. This study was designed to assess the effect of angiotensin-converting enzyme
inhibition and beta-adrenoreceptor blockade on established ventricular remodeling …

Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival and Ventricular Enlargement …

MA Pfeffer, E Braunwald, LA Moyé… - New England journal …, 1992 - Mass Medical Soc
Background. Left ventricular dilatation and dysfunction after myocardial infarction are major
predictors of death. In experimental and clinical studies, long-term therapy with the …