Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants

BG Fisher, A Thankamony, IA Hughes… - Human …, 2016 - academic.oup.com
STUDY QUESTION What is the relationship between maternal paracetamol intake during
the masculinisation programming window (MPW, 8–14 weeks of gestation) and male infant …

Urinary paracetamol and time-to-pregnancy

MM Smarr, KL Grantz, R Sundaram… - Human …, 2016 - academic.oup.com
STUDY QUESTION Is preconception urinary paracetamol (acetaminophen) associated with
time-to-pregnancy (TTP)? SUMMARY ANSWER Higher urinary paracetamol concentrations …

Intrauterine exposure to paracetamol and aniline impairs female reproductive development by reducing follicle reserves and fertility

JB Holm, S Mazaud-Guittot… - Toxicological …, 2016 - academic.oup.com
Studies report that fetal exposure to paracetamol/acetaminophen by maternal consumption
can interfere with male reproductive development. Moreover, recent biomonitoring data …

[HTML][HTML] EDC IMPACT: Is exposure during pregnancy to acetaminophen/paracetamol disrupting female reproductive development?

FS Arendrup, S Mazaud-Guittot, B Jégou… - Endocrine …, 2018 - ec.bioscientifica.com
Concern has been raised over chemical-induced disruption of ovary development during
fetal life resulting in long-lasting consequences only manifesting themselves much later …

[HTML][HTML] Association between paracetamol use during pregnancy and perinatal outcomes: Prospective NISAMI cohort

CT de Castro, M Pereira, DB Dos Santos - PloS one, 2022 - journals.plos.org
Background Paracetamol is widely used to manage fever and pain during pregnancy
worldwide. However, paracetamol may affect the pregnant woman and fetus, once this drug …

Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother–child pairs

DV Lind, KM Main, HB Kyhl, DM Kristensen… - Human …, 2017 - academic.oup.com
STUDY QUESTION Is maternal use of mild analgesics in pregnancy associated with
anogenital distance (AGD)—the distance from the anus to the genitals—in the offspring …

Acetaminophen (paracetamol) exposure during pregnancy and pubertal development in boys and girls from a nationwide puberty cohort

A Ernst, N Brix, LLB Lauridsen, J Olsen… - American Journal of …, 2019 - academic.oup.com
This study explored the association between exposure to acetaminophen during pregnancy
and pubertal development using data from 15,822 boys and girls in the longitudinal Puberty …

[HTML][HTML] Long-term safety of prenatal and neonatal exposure to paracetamol: a systematic review

R Patel, K Sushko, J van den Anker… - International Journal of …, 2022 - mdpi.com
Introduction: Paracetamol is the most commonly used antipyretic and analgesic in
pregnancy. It is also increasingly used off-label in the neonatal intensive care unit. Despite …

Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study

RE Brandlistuen, E Ystrom, I Nulman… - International journal …, 2013 - academic.oup.com
Background Paracetamol is used extensively during pregnancy, but studies regarding the
potential neurodevelopmental sequelae of foetal paracetamol exposure are lacking. Method …

Assessing the impact of in-utero exposures: potential effects of paracetamol on male reproductive development

KR Kilcoyne, RT Mitchell - Archives of Disease in Childhood, 2017 - adc.bmj.com
Human male reproductive disorders (cryptorchidism, hypospadias, testicular cancer and low
sperm counts) are common and some may be increasing in incidence worldwide. These …