The widespread use of ion-selective electrode causes the reference range of the anion gap
(AG) to be lowered from 8–16 to 3–11 mmol/l. The use of the outdated reference range (8 …

Anion gap (AG) is a calculated value commonly used in clinical practice. It approximates the
difference between the concentration of unmeasured anions (UA) and unmeasured cations …

The anion gap in the serum is useful in the interpretation of acid-base disorders and in the
diagnosis of other conditions. In the early 1980s, ion-selective electrodes for specific ionic …

Aim: The aim of our study was to do an agreement analysis of two different laboratory
methods used to measure electrolytes ie, between the ISE based Beckman Coulter …

We wish to comment on reference intervals for the serum anion gap and osmolality. The
serum anion gap, which is most commonly defined as AG Na-Cl-TCO2, traditionally has had …

Background It is sometimes necessary for the laboratory to re‐test samples for critical serum
electrolyte levels. It is important to assure reproducibility of results when testing is performed …

We have identified rare (approximately 0.2% of all samples), but clinically significant,
discrepancies between serum or plasma sodium concentrations measured with the Kodak …

Three interlaboratory round-robin studies (RR1, RR2, and RR3) were conducted to identify a
serum-based reference material that would aid in the standardization of direct ion-selective …

The physiological approach is a serviceable method for interpreting acid-base disorders [1,
2]. The anion gap can be helpful in narrowing the differential diagnosis in a patient with …

Background Using flame photometry technique in the 1970s, the normal value of anion gap
(AG) was determined to be 12±4 meq/L. However, with introduction of the autoanalyzers …