Cerebellar and hippocampal activation during eyeblink conditioning depends on the experimental paradigm: a MEG study

P Kirsch, C Achenbach, M Kirsch, M Heinzmann… - Neural …, 2003 - hindawi.com
The cerebellum and the hippocampus are key structures for the acquisition of conditioned
eyeblink responses. Whereas the cerebellum seems to be crucial for all types of eyeblink …

Eyeblink conditioning in healthy adults: a positron emission tomography study

KL Parker, NC Andreasen, D Liu, JH Freeman… - The Cerebellum, 2012 - Springer
Eyeblink conditioning is a paradigm commonly used to investigate the neural mechanisms
underlying motor learning. It involves the paired presentation of a tone-conditioning stimulus …

Classical conditioning of timed motor responses: Neural coding in cerebellar cortex and cerebellar nuclei

HJ Boele, MM Ten Brinke, CI De Zeeuw - The neuronal codes of the …, 2016 - Elsevier
During delay classical conditioning of the eyelid response, which models both associative
learning and motor learning, the essential memory is formed in the cerebellum. In this …

[HTML][HTML] Cerebellar and extracerebellar involvement in mouse eyeblink conditioning: the ACDC model

HJ Boele, SKE Koekkoek, CI De Zeeuw - Frontiers in Cellular …, 2010 - frontiersin.org
Over the past decade the advent of mouse transgenics has generated new perspectives on
the study of cerebellar molecular mechanisms that are essential for eyeblink conditioning …

Cerebellar cortex and cerebellar nuclei are concomitantly activated during eyeblink conditioning: a 7T fMRI study in humans

M Thürling, F Kahl, S Maderwald… - Journal of …, 2015 - Soc Neuroscience
There are controversies whether learning of conditioned eyeblink responses primarily takes
place within the cerebellar cortex, the interposed nuclei, or both. It has also been suggested …

The importance of cerebellar cortex and facial nucleus in acquisition and retention of eyeblink/NM conditioning: Evidence for critical unilateral regulation of the …

RE Clark, AA Zhang, DG Lavond - Neurobiology of learning and memory, 1997 - Elsevier
Experiment 1 examined acquisition of the classically conditioned eyeblink response in
rabbits (Oryctolagus cuniculus) during reversible cooling lesions of the cerebellar cortex …

Trace eyeblink conditioning in human subjects with cerebellar lesions

M Gerwig, K Haerter, K Hajjar, A Dimitrova… - Experimental brain …, 2006 - Springer
Trace eyeblink conditioning was investigated in 31 patients with focal cerebellar lesions and
19 age-matched controls. Twelve patients presented with lesions including the territory of …

Modulation of 7 T fMRI signal in the cerebellar cortex and nuclei during acquisition, extinction, and reacquisition of conditioned eyeblink responses

TM Ernst, M Thürling, S Müller, F Kahl… - Human Brain …, 2017 - Wiley Online Library
Classical delay eyeblink conditioning is likely the most commonly used paradigm to study
cerebellar learning. As yet, few studies have focused on extinction and savings of …

Neural substrates of eyeblink conditioning: acquisition and retention

KM Christian, RF Thompson - Learning & memory, 2003 - learnmem.cshlp.org
Classical conditioning of the eyeblink reflex to a neutral stimulus that predicts an aversive
stimulus is a basic form of associative learning. Acquisition and retention of this learned …

The cerebellum and eye-blink conditioning: learning versus network performance hypotheses

V Bracha, S Zbarska, K Parker, A Carrel, G Zenitsky… - Neuroscience, 2009 - Elsevier
Classical conditioning of the eye-blink reflex in the rabbit is a form of motor learning that is
uniquely dependent on the cerebellum. The cerebellar learning hypothesis proposes that …