Induced pluripotent stem cell (iPSCs) and their application in immunotherapy
Z Jiang, Y Han, X Cao - Cellular & molecular immunology, 2014 - nature.com
The ever-improving technology to generate induced pluripotent stem cells (iPSCs) has
increased their potential use as novel candidates for disease modeling, drug screening …
increased their potential use as novel candidates for disease modeling, drug screening …
[HTML][HTML] Recent technological updates and clinical applications of induced pluripotent stem cells
Induced pluripotent stem cells (iPSCs) were first described in 2006 and have since emerged
as a promising cell source for clinical applications. The rapid progression in iPSC …
as a promising cell source for clinical applications. The rapid progression in iPSC …
Roadblocks in the Path of iPSC to the Clinic
E Garreta, S Sanchez, J Lajara, N Montserrat… - Current transplantation …, 2018 - Springer
Abstract Purpose of Review The goal of this paper is to highlight the major challenges in the
translation of human pluripotent stem cells into a clinical setting. Recent Findings Innate …
translation of human pluripotent stem cells into a clinical setting. Recent Findings Innate …
Strategies to generate induced pluripotent stem cells
M Hayes, N Zavazava - … Stem Cell Immunobiology: Methods and Protocols, 2013 - Springer
The isolation of embryonic stem cells (ESCs) has furthered our understanding of normal
embryonic development and fueled the progression of stem cell derived therapies. However …
embryonic development and fueled the progression of stem cell derived therapies. However …
Autologous induced pluripotent stem cell–based cell therapies: Promise, progress, and challenges
M Madrid, C Sumen, S Aivio, N Saklayen - Current protocols, 2021 - Wiley Online Library
The promise of human induced pluripotent stem cells (iPSCs) lies in their ability to serve as
a starting material for autologous, or patient‐specific, stem cell–based therapies. Since the …
a starting material for autologous, or patient‐specific, stem cell–based therapies. Since the …
[HTML][HTML] Methods of induced pluripotent stem cells for clinical application
T Seki, K Fukuda - World journal of stem cells, 2015 - ncbi.nlm.nih.gov
Reprograming somatic cells using exogenetic gene expression represents a
groundbreaking step in regenerative medicine. Induced pluripotent stem cells (iPSCs) are …
groundbreaking step in regenerative medicine. Induced pluripotent stem cells (iPSCs) are …
Derivation of human induced pluripotent stem cell (iPSC) lines and mechanism of pluripotency: historical perspective and recent advances
A Chhabra - Stem Cell Reviews and Reports, 2017 - Springer
Derivation of human embryonic stem cell (hES) lines in 1998 was not only a major
technological breakthrough in the field of regenerative medicine; it also triggered a …
technological breakthrough in the field of regenerative medicine; it also triggered a …
Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions
Recently, induced pluripotent stem cells (iPSCs) were established as promising cell sources
for revolutionary regenerative therapies. The initial culture system used for iPSC generation …
for revolutionary regenerative therapies. The initial culture system used for iPSC generation …
[HTML][HTML] Pluripotent stem cell-based cell therapies: Current applications and future prospects
G Wang, P Heimendinger, RA Ramelmeier… - Current Opinion in …, 2022 - Elsevier
Recently, there has been a major uptick in the research and clinical development of
pluripotent stem cells (PSCs). This is due to human PSC's unique properties of unlimited self …
pluripotent stem cells (PSCs). This is due to human PSC's unique properties of unlimited self …
Pluripotent stem cells: immune to the immune system?
Human embryonic stem cells (hESCs), initially thought to be immune privileged cells, are
now known to be susceptible to immune recognition. Human induced pluripotent stem cells …
now known to be susceptible to immune recognition. Human induced pluripotent stem cells …