Objective: Evolving evidence of anti-inflammatory effects is observed in patients with
rheumatoid arthritis or ulcerative colitis following periodic adsorptive granulocyte and …

Objective: Dramatic improvements in clinical symptoms of rheumatoid arthritis and ulcerative
colitis were observed after patients received granulocyte and monocyte adsorptive …

Granulocyte and monocyte adsorptive apheresis (GMA) using a column filled with cellulose
acetate (CA) beads (carriers) has been associated with a significant clinical efficacy in …

To elucidate the molecular mechanisms involved in the therapeutic effects of
granulocyte/monocyte adsorption apheresis, changes were investigated in the cytokine …

In active rheumatoid arthritis, large numbers of granulocytes and macrophages are found in
the inflamed joints. These leucocytes can promote inflammation and tissue injury by …

Our aim was to understand the mechanism of immunological changes associated with the
use of an adsorptive-type extracorporeal device (Adacolumn) that has been developed for …

Recruitment of neutrophils into tissue occurs in several pathologic processes such as
inflammation, atherosclerosis, thrombosis, and ischemia. In inflammation, the adherence of …

Serum hepatocyte growth factor (HGF) is rapidly increased in patients suffering from various
tissue injuries including arterial occlusive diseases. However, the cellular sources of the …

To investigate if granulocyte and monocyte apheresis mitigates the symptoms of rheumatoid
arthritis (RA), and influences production of panmyelocytes (CD15+ CD16–cells) at the bone …

We investigated the hypothesis that CD54 (intercellular adhesion molecule-1) expressed on
hepatocytes will support beta2-integrin (CD18)-dependent adhesion of neutrophils. An in …