Identifying factors that influence fetal growth in a sex-specific manner can help unravel
mechanisms that explain sex differences in adverse neonatal outcomes and in-utero origins …

Disruption of physiological aging of the placenta can lead to pregnancy complications and
increased risk for cardiometabolic diseases during childhood and adulthood. Maternal …

Disruption of physiological ageing of the placenta is associated with obstetric complications.
Altered lipid metabolism is a known trigger of tissue ageing, but the effect of maternal …

Social determinants of health (SDoH) are defined as the conditions in which people are
born, grow, live, work, and age. The distribution of these conditions is influenced by …

Background Birthweight marks an important milestone of health across the lifespan,
including cardiometabolic disease risk in later life. The placenta, a transient organ at the …

Being born small (SGA) or large for gestational age (LGA) is associated with adverse birth
outcomes and metabolic diseases in later life of the offspring. It is known that aberrations in …

Importance Preeclampsia, gestational hypertension, and gestational diabetes, the most
common pregnancy complications, are associated with substantial morbidity and mortality in …

Aim: To determine whether dynamic DNA methylation changes in the human placenta can
be used to predict gestational age. Materials & methods: Publicly available placental DNA …

The placenta undergoes many changes throughout gestation to support the evolving needs
of the foetus. There is also a growing appreciation that male and female foetuses develop …

Inherent genetic programming and environmental factors affect fetal growth in utero.
Epidemiologic data in growth-altered fetuses, either intrauterine growth restricted (IUGR) or …