We have evaluated whether the arachidonic acid cascade may be involved in the folding
and fusion of the penis and scrotum in masculine differentiation, a possibility raised by …

The present study was designed to test the hypothesis that the stimulation of arachidonic
acid prostaglandins (PG) mediates the masculinizing effects of testosterone in the fetal …

IN ANY CONSIDERATION of the effects of androgens on the fetal organism, it is important
that the term" androgen" be defined. An androgen is usually regarded as a steroid which, in …

TESTOSTERONE administration during mid-pregnancy caused in♀♀ the persistence of
Wolifian ducts and the differentiation of♀ accessory gland. Postnatal treatment of these♀♀ …

This study tested the hypothesis that testis/reproductive tract abnormalities induced in the rat
by neonatal treatment with diethylstilbestrol (DES) result from disturbance of the androgen …

Administration of exogenous androgen to neonatal female rats induces a syndrome of
sterility characterized by anovulation and persistent vaginal cornification. As a step in the …

Exposure of fetuses to some hormonally active agents may imprint permanent changes on
the action of related hormones. These changes can be detected in adulthood as a …

Exposure of the developing female brain to a 5α-dihydrotestosterone surge on day 18 of
gestation resulted in defeminization and slight masculinization of the brain. In contrast …

In mammals males are the heterogametic sex, and the Y chromosome codes for
differentiation of the gonads into testes. With the exception of the primary sexual …

To investigate the role of neonatal androgen stimulation in the development of the potential
for masculine and feminine sexual behavior in the mouse, different groups of mice were …