Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis

C Agostini, C Gurrieri - Proceedings of the American Thoracic …, 2006 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible fibrosing lung disease of
unknown etiology and with an unfavorable outcome, leading ultimately to death due to …

Idiopathic pulmonary fibrosis: new insights in its pathogenesis

A Pardo, M Selman - The international journal of biochemistry & cell biology, 2002 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a unique type of chronic fibrosing lung disease of
unknown etiology. The sequence of the pathogenic mechanisms is unknown, but the …

Integrating mechanisms of pulmonary fibrosis

TA Wynn - Journal of Experimental Medicine, 2011 - rupress.org
Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …

[HTML][HTML] Pulmonary fibrosis: patterns and perpetrators

PW Noble, CE Barkauskas… - The Journal of clinical …, 2012 - Am Soc Clin Investig
Pulmonary fibrosis occurs in a variety of clinical settings, constitutes a major cause of
morbidity and mortality, and represents an enormous unmet medical need. However, the …

Immune mechanisms in pulmonary fibrosis

S Kolahian, IE Fernandez, O Eickelberg… - American journal of …, 2016 - atsjournals.org
Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis, represents a chronic and
progressive disease with high mortality and limited therapeutic options. Excessive …

[HTML][HTML] Molecular and cellular mechanisms of pulmonary fibrosis

NW Todd, IG Luzina, SP Atamas - Fibrogenesis & tissue repair, 2012 - Springer
Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …

Pathogenetic pathways and novel pharmacotherapeutic targets in idiopathic pulmonary fibrosis

KM Antoniou, A Pataka, D Bouros… - Pulmonary pharmacology …, 2007 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a poorly understood disease that usually leads to death
within 5 years of diagnosis. Despite our better understanding of IPF pathogenesis, the …

[PDF][PDF] Molecular mechanisms of pulmonary fibrosis

A Pardo, M Selman - Front Biosci, 2002 - article.imrpress.com
Introduction 3. Lessons from the inflammatory pathway 3.1. The paradigm of type 1 or type 2
cytokine network commitment 3.2. Chemokines 3.2. 1. Chemokines in inflammatory/fibrotic …

Molecular mechanisms of and possible treatment strategies for idiopathic pulmonary fibrosis

M Gharaee-Kermani, SH Phan - Current pharmaceutical design, 2005 - ingentaconnect.com
Pulmonary fibrosis is characterized by lung inflammation and abnormal tissue repair,
resulting in the replacement of normal functional tissue with an abnormal accumulation of …

Re-evaluation of fibrogenic cytokines in lung fibrosis

M Kelly, M Kolb, P Bonniaud… - Current pharmaceutical …, 2003 - ingentaconnect.com
Idiopathic Pulmonary Fibrosis (IPF) is a chronic interstitial lung disease which results in end-
stage fibrosis. The pathogenesis is believed to be related to a dysregulation in cross-talk …