非损伤性功能成像技术: 正电子发射断层扫描术, 磁共振波谱分析和动态对比增强磁共振影像学
RE Port - 中国临床药理学与治疗学, 2007 - manu41.magtech.com.cn
当前在医药工业中越来越关注将非损伤性功能成像技术作为潜在的病人体内药物作用早期检测
技术. 正电子发射断层扫描术可监测组织中放射标记的药物和其代谢物的绝对浓度 …
技术. 正电子发射断层扫描术可监测组织中放射标记的药物和其代谢物的绝对浓度 …
Noninvasive functional imaging techniques: positron emission tomography (PET), magnetic resonance spectroscopy (MRS), dynamic contrast-enhanced magnetic …
RE Port - Chinese Journal of Clinical Pharmacology and …, 2007 - manu41.magtech.com.cn
In the pharmaceutical industry, there is currently increasing interest in noninvasive functional
imaging techniques as potential early indicators of drug effects in patients. PET allows one …
imaging techniques as potential early indicators of drug effects in patients. PET allows one …
PET 示踪剂的临床应用及研究进展
张宝石， 周乃康， 张锦明， 于长海 - 中国医药导刊, 2011 - cqvip.com
正电子发射型断层显像术(Positron Emission Tomography, PET) 是20 世纪90
年代后期蓬勃发展起来一项功能性显像诊断技术[1]. 目前, 这一功能性影像技术在心脑血管疾病 …
年代后期蓬勃发展起来一项功能性显像诊断技术[1]. 目前, 这一功能性影像技术在心脑血管疾病 …
Imaging as a tool in drug development.
T Strack - Drugs of Today (Barcelona, Spain: 1998), 2007 - europepmc.org
Medical imaging has experienced a huge increase in exploratory technologies over the past
20 to 30 years. From drug discovery to drug development to routine clinical practice, the …
20 to 30 years. From drug discovery to drug development to routine clinical practice, the …
The unique potential for noninvasive imaging in modernizing drug development and in transforming therapeutics: PET/MRI/MRS
W Wolf - Pharmaceutical research, 2011 - Springer
The classical principles of effective pharmacotherapy requires that the patient to be treated
receive the right drug, at the right rate, at the right dose, and at the right site. Knowing what is …
receive the right drug, at the right rate, at the right dose, and at the right site. Knowing what is …
微PET 在临床前研究中的应用
刘卓然 - 临床医药实践, 2012 - cqvip.com
正电子发射型断层扫描(PET) 技术是一种可以测定生物体内特定的放射性示踪剂的分布与浓聚
的影像学检查技术, 作为功能显像的重要工具, 已经广泛应用于临床肿瘤, 心脏和神经疾病等学科 …
的影像学检查技术, 作为功能显像的重要工具, 已经广泛应用于临床肿瘤, 心脏和神经疾病等学科 …
Noninvasive methods to study drug distribution
RE Port, W Wolf - Investigational new drugs, 2003 - Springer
Positron emission tomography (PET) and nuclear magnetic resonance spectroscopy (MRS)
are two techniques that allow the noninvasive monitoring of drug distribution in living …
are two techniques that allow the noninvasive monitoring of drug distribution in living …
正电子发射断层显像对药物研究及开发的价值
朱朝晖 - 首都医药, 2003 - cqvip.com
随着正电子发射断层显像(PET) 技术的迅速发展, 其对药物研究及开发的价值正越来越受到重视.
PET 可以定量测量药物在活体内的分布及随时间的变化. 既可以用发射正电子的核素直接标记 …
PET 可以定量测量药物在活体内的分布及随时间的变化. 既可以用发射正电子的核素直接标记 …
[HTML][HTML] PET 分子显像技术在药代动力学研究中的应用
李新平， 王燕， 卢国， 李艳静， 于雪， 侯文彬… - 国际放射医学核医学 …, 2019 - ijrmnm.com
药代动力学是药理学研究的重要内容之一, 对于指导临床合理用药, 预防药物不良反应,
探究药物的作用机制和药物相互作用等具有重要意义. PET 分子显像技术可以动态监测体内生理 …
探究药物的作用机制和药物相互作用等具有重要意义. PET 分子显像技术可以动态监测体内生理 …
In vivo magnetic resonance imaging and spectroscopy in pharmacological research: assessment of morphological, physiological and metabolic effects of drugs
M Rudin, N Beckmann, A Mir, A Sauter - European journal of …, 1995 - Elsevier
Nuclear magnetic resonance methods are becoming recognized tools not only in medicine
but also in experimental pharmacological research. The most widely used modality …
but also in experimental pharmacological research. The most widely used modality …