Closing the gap between adverse health effects of aluminum and its mechanisms of action
still represents a huge challenge. Cholinergic dysfunction has been implicated in neuronal …

The ability of aluminum to inhibit the (Na+/K+) ATPase activity has been observed by several
investigators. The (Na+/K+) ATPase is characterized by a complex molecular heterogeneity …

Aluminium is neurotoxic in humans and has been implicated in several neurological
disorders. Chronic use of buffered aspirins, as aspegic, would likely constitute the major …

In the present study, we analyzed how aluminium and oxidative stress induced by
ascorbate/Fe 2+ affect the mechanisms related with the cholinergic system in a crude …

Cholinergic functions of the central nervous system (CNS) mainly depend on the
neurotransmitter acetylcholine (ACh). After release from presynaptic nerve terminals …

Aluminum salts or doses that are unlikely in the human system have been employed in
toxicity studies and much attention had been focused on the secondary target (neurons) of …

Recent studies have demonstrated that brain may be considered as the target for aluminium
(Al) toxicity, resulting in development of neurodegenerative and neurodevelopmental …

Aluminum, a metal without redox capacity in biological systems, potentiates the stimulation
of lipid peroxidation induced by Fe2+. In this study the interactions between aluminum and …

Abstract The effects of Cd 2+, Mn 2+ and Al 3+ on rat brain synaptosomal sodium-potassium-
activated and magnesium-activated adenosine triphosphatase (Na-K-ATPase and Mg …

Aluminum (Al) has been implicated in neurotoxic syndromes in several conditions, including
Alzheimer's disease (AD). The developmental stage of the mammalian brain most …