Clinical predictors of failing one dose of methotrexate for ectopic pregnancy after in vitro fertilization

PC Brady, SA Missmer, LV Farland… - Journal of assisted …, 2017 - Springer
Purpose The aim of this study is to investigate the clinical predictors of failure of a single
dose of methotrexate (MTX) for management of ectopic pregnancy after in vitro fertilization …

Methotrexate treatment of ectopic pregnancy does not impact ovarian reserve or clinical outcome, regardless of the duration of time since exposure

L Sekhon, J Rodriguez-Purata, JA Lee… - Fertility and …, 2016 - fertstert.org
Objective Methotrexate (MTX) is a minimally invasive treatment for ectopic pregnancy. As it
targets rapidly dividing cells, there is concern it may affect proliferating germinal cells in the …

Success of the two-dose methotrexate protocol for treatment of ectopic pregnancy in women with a history of prior ectopic pregnancy.

JF McLaren, KT Barnhart, MD Sammel… - The Journal of …, 2014 - europepmc.org
Objective Women with prior ectopic pregnancy (EP) have an increased failure rate when
treated with single-dose methotrexate (MTX) for subsequent EP. We sought to determine …

[HTML][HTML] Does methotrexate administration for ectopic pregnancy after in vitro fertilization impact ovarian reserve or ovarian responsiveness?

CE Boots, RL Gustofson, EC Feinberg - Fertility and sterility, 2013 - Elsevier
Objective To evaluate the effects of methotrexate (MTX) on the future fertility of women
undergoing IVF by comparing ovarian reserve and ovarian responsiveness in the IVF cycle …

Single dose methotrexate for treatment of ectopic pregnancy: risk factors for treatment failure

M Eskandar - 2007 - tspace.library.utoronto.ca
Objective: To identify risk factors for single dose methotrexate (MTX) failure among patients
treated for ectopic pregnancies. Design: Retrospective cohort. Materials and methods …

[HTML][HTML] Predictors of treatment failure for ectopic pregnancy treated with single-dose methotrexate

A Tawfiq, AF Agameya, P Claman - Fertility and sterility, 2000 - Elsevier
Objective: To determine variables that predict treatment failure after methotrexate (MTX)
treatment of ectopic pregnancy. Design: Retrospective cohort study. Setting: Canadian …

[HTML][HTML] Predictive factors of failure in management of ectopic pregnancy with single-dose methotrexate: a general population-based analysis from the Auvergne …

B Rabischong, X Tran, A Abi Sleiman, D Larraín… - Fertility and sterility, 2011 - Elsevier
In a general population setting, the existence of a learning curve for treatment of ectopic
pregnancy with single-dose methotrexate has been demonstrated, because a significant …

[HTML][HTML] Systemic methotrexate to treat ectopic pregnancy does not affect ovarian reserve

B Oriol, A Barrio, A Pacheco, J Serna, JL Zuzuarregui… - Fertility and sterility, 2008 - Elsevier
OBJECTIVE: To evaluate whether methotrexate (MTX) compromises ovarian reserve and
future reproductive outcome in women undergoing assisted reproductive technology (ART) …

Early prediction of methotrexate treatment outcome in tubal ectopic pregnancy based on days 0 and 4 human chorionic gonadotropin levels

N Shatkin Hamish, M Wolf, R Tendler… - Journal of Obstetrics …, 2020 - Wiley Online Library
Aim Methotrexate (MTX) is an efficient treatment for ectopic pregnancy, used according to
'single‐dose'protocol. Treatment success is evaluated on days 4 and 7 after dose …

A validation of the most commonly used protocol to predict the success of single-dose methotrexate in the treatment of ectopic pregnancy

E Kirk, G Condous, B Van Calster, Z Haider… - Human …, 2007 - academic.oup.com
BACKGROUND: Currently, the likely success of single-dose methotrexate (MTX)(50 mg/m2)
for the treatment of ectopic pregnancy is indicated by a> 15% decrease in hCG from days 4 …