Comparison of autoantibody specificities between traditional and bead‐based assays in a large, diverse collection of patients with systemic lupus erythematosus and …

BF Bruner, JM Guthridge, R Lu, G Vidal… - Arthritis & …, 2012 - Wiley Online Library
Objective Replacement of standard immunofluorescence methods with bead‐based assays
for antinuclear antibody (ANA) testing is a new clinical option. The aim of this study was to …

Comparison between multiplex assays for autoantibody detection in systemic lupus erythematosus

JG Hanly, L Su, V Farewell, MJ Fritzler - Journal of immunological methods, 2010 - Elsevier
The performance of immunoassays for the detection of autoantibodies is of critical
importance to the diagnosis and assessment of patients with systemic lupus erythematosus …

Autoantibody profiling to identify individuals at risk for systemic lupus erythematosus

AE Wandstrat, F Carr-Johnson, V Branch, H Gray… - Journal of …, 2006 - Elsevier
The objective of this study was to determine the prevalence of lupus-related autoimmunity in
a community-based cohort of over 3000 subjects, using a rheumatology registry as a …

Measurement of autoantibodies using multiplex methodology in patients with systemic lupus erythematosus

JG Hanly, K Thompson, G McCurdy, L Fougere… - Journal of …, 2010 - Elsevier
Autoantibodies are central to the diagnosis and assessment of systemic lupus
erythematosus (SLE). A recent technique for the measurement of autoantibodies utilizes …

Autoantibodies in systemic lupus erythematosus: comparison of historical and current assessment of seropositivity

A Ippolito, DJ Wallace, D Gladman, PR Fortin… - Lupus, 2011 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is characterized by multiple autoantibodies and
complement activation. Recent studies have suggested that anti-nuclear antibody (ANA) …

Familial aggregation and linkage analysis of autoantibody traits in pedigrees multiplex for systemic lupus erythematosus

PS Ramos, JA Kelly, C Gray-McGuire, GR Bruner… - Genes & …, 2006 - nature.com
Autoantibodies are clinically relevant biomarkers for numerous autoimmune disorders. The
genetic basis of autoantibody production in systemic lupus erythematosus (SLE) and other …

[HTML][HTML] Multiple autoantibodies display association with lymphopenia, proteinuria, and cellular casts in a large, ethnically diverse SLE patient cohort

R Lu, JM Robertson, BF Bruner, JM Guthridge… - Autoimmune …, 2012 - hindawi.com
Purpose. This study evaluates high-throughput autoantibody screening and determines
associated systemic lupus erythematosus (SLE) clinical features in a large lupus cohort …

Identification of autoantibodies associated with systemic lupus erythematosus

Y Lim, DY Lee, S Lee, SY Park, J Kim, B Cho… - Biochemical and …, 2002 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the
presence of antinuclear antibodies. We performed serological analysis of cDNA expression …

[HTML][HTML] Two major autoantibody clusters in systemic lupus erythematosus

KH Ching, PD Burbelo, C Tipton, C Wei, M Petri, I Sanz… - PloS one, 2012 - journals.plos.org
Systemic lupus erythematosus is a chronic autoimmune disease of complex clinical
presentation and etiology and is likely influenced by numerous genetic and environmental …

Information on diagnosis and management of systemic lupus erythematosus derived from the routine measurement of 8 nuclear autoantibodies.

GP Ignat, AC Rat, JJ Sychra, J Vo, J Varga… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: To determine the value of routine measurement of a panel of 8 nuclear
autoantibodies (ANA/8) for the diagnosis and management of patients with systemic lupus …