As vaccine-induced immunity and protection following natural pertussis infection wane over
time, adults and adolescents may develop pertussis and become transmitters to unprotected …

Background Pertussis in adults and adolescents could be reduced by replacing traditional
tetanus and diphtheria (Td) boosters with reduced-antigen-content diphtheria–tetanus …

At 60 months post-vaccination, adults (mean age 45.6 years) randomised to receive
combined reduced-antigen-content diphtheria–tetanus and acellular pertussis vaccine …

A trial to compare the reactogenicity and immunogenicity of a reduced antigen content
diphtheria–tetanus–acellular pertussis (dTpa) vaccine with diphtheria–tetanus–whole-cell …

Background Over the last decades, pertussis showed periodic increases in its incidence
among adults, despite being a vaccine-preventable disease. Methods This phase III …

Background. Booster vaccination against tetanus and diphtheria at 10-year intervals is
commonly recommended. Reduced antigen content diphtheria and tetanus toxoids and …

The aim of this assessor-blinded trial was to compare the immunogenicity and reactogenicity
of a candidate diphtheria, tetanus toxoids and acellular pertussis vaccine with reduced …

Background: The rising incidence of pertussis amongst adults and adolescents in
industrialised countries could be reduced by replacing tetanus and diphtheria (Td) boosters …

Reduced-antigen-content diphtheria–tetanus–acellular-pertussis (dTpa) vaccines are
predominantly recommended for once-in-a-lifetime use. A second dTpa (Boostrix™ …

Introduction The immunogenicity and safety of one dose of Tdap-IPV (tetanus, diphtheria,
acellular pertussis and inactivated poliomyelitis vaccine) and two doses of Td-IPV (tetanus …