Evaluation of ERBB2 gene status and chromosome 17 anomalies in male breast cancer

RR Fonseca, AR Tomás, S André… - The American journal of …, 2006 - journals.lww.com
Male breast cancer (MBC) is an uncommon neoplasm that shares several biologic
characteristics with its female counterpart. In the latter, abnormalities in the expression …

[HTML][HTML] Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situhybridization and …

M Salido, I Tusquets, JM Corominas, M Suarez… - Breast Cancer …, 2005 - Springer
Introduction One of the most common genetic aberrations associated with breast cancer is
the amplification and overexpression of the ERBB2 proto-oncogene located at chromosome …

Classification of HER2-negative breast cancers by ERBB2 copy number alteration status reveals molecular differences associated with chromosome 17 gene …

JW Loh, AH Lim, JY Chan… - Therapeutic Advances in …, 2023 - journals.sagepub.com
Background: Recently, HER2-negative breast cancers have been reclassified by protein
expression into 'HER2-low'and 'HER2-zero'subgroups, but the consideration of HER2-low …

Oncogenes and male breast carcinoma: c-erbB-2 and p53 coexpression predicts a poor survival

A Pich, E Margaria, L Chiusa - Journal of clinical oncology, 2000 - ascopubs.org
PURPOSE: To investigate the prognostic value of biomarkers in male breast carcinoma
(MBC). PATIENTS AND METHODS: Fifty patients (mean age, 62.2 years) with invasive …

[HTML][HTML] Male breast carcinoma: correlation of ER, PR, Ki-67, Her2-Neu, and p53 with treatment and survival, a study of 65 cases

J Wang-Rodriguez, K Cross, S Gallagher… - Modern pathology, 2002 - Elsevier
Male breast cancer is rare, and experience of it in any single institution is limited. Our current
understanding regarding its biology, natural history, and treatment strategies has been …

[HTML][HTML] Therapeutic strategies in male breast cancer: clinical implications of chromosome 17 gene alterations and molecular subtypes

HU Schildhaus, L Schroeder, S Merkelbach-Bruse… - The Breast, 2013 - Elsevier
Male breast cancer (MBC) is a rare disease. To date, therapy is mainly based on studies and
clinical experiences with breast cancer in women. Only little is known about molecular typing …

Prognostic variables in male breast cancer

JL Clark, PL Nguyen, WB Jaszcz, A Jatoi… - The American …, 2000 - journals.sagepub.com
The prognostic role of ploidy status, S phase fraction, estrogen and progesterone receptor
status, and the expression of p 53 and erbB-2 protein in male breast carcinoma (MBC) …

[HTML][HTML] Clinicopathologic characteristics and survival of male breast cancer

D Liu, G Xie, M Chen - International journal of clinical oncology, 2014 - Springer
Backgrounds Male breast cancer (MBC) is a rare disease and accounts for< 1% of all breast
cancers. Methods We retrospectively analyzed clinicopathologic characteristics and …

[HTML][HTML] Characterisation of male breast cancer: a descriptive biomarker study from a large patient series

MP Humphries, S Sundara Rajan, H Honarpisheh… - Scientific reports, 2017 - nature.com
Male breast cancer (MBC) is rare. We assembled 446 MBCs on tissue microarrays and
assessed clinicopathological information, together with data from 15 published studies …

Genetic alterations on chromosome 17 in human breast cancer: relationships to clinical features and DNA ploidy

M Watatani, K Nagayama, Y Imanishi… - Breast cancer research …, 1993 - Springer
We analyzed DNA from 105 primary breast cancers to assess amplification of the ERBB2
gene and loss of heterozygosity (LOH) on chromosome 17 using 4 polymorphic markers …