Alpha‐1 adrenoceptor subtypes (high, low) in human benign prostatic hypertrophy tissue according to the affinities for prazosin

M Takeda, A Hatano, T Komeyama, T Koizumi… - The …, 1997 - Wiley Online Library
BACKGROUND A novel classification of α‐1 adrenoceptor subtypes (High, Low) was
applied to human benign prostatic hypertrophy (BPH) tissue. METHODS Human BPH …

Pharmacological characterization of α1‐adrenoceptor subtypes in the human prostate: functional and binding studies

I Muramatsu, M Oshita, T Ohmurs… - British journal of …, 1994 - Wiley Online Library
Objective To characterize the α1,‐adrenoceptor subtypes of the human benignly enlarged
prostate using functional and binding studies. Material and methods Strips of prostatic tissue …

Binding and Functional Properties of Alpha1 Drenoceptors in Different Regions of the Human Prostate

H Lepor, R Tang, S Meretyk, E Shapiro - The Journal of urology, 1993 - Elsevier
The objective of the present study was to determine the density and functional properties of
alpha 1 adrenoceptors in different regions of the human prostate. Binding and functional …

Alpha-1 adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy.

S Yamada, N Ashizawa, H Ushijima… - … of Pharmacology and …, 1987 - ASPET
Alpha-1 adrenoceptors in hypertrophied prostates of humans were characterized by a
binding assay using [3H] prazosin as a radioligand. Specific [3H] prazosin binding in …

α1‐Adrenoceptor Subtypes in Bovine Prostate

K Maruyama, H Tsuchihashi, S Baba… - Journal of pharmacy …, 1992 - Wiley Online Library
The object of this study was to examine the existence and characteristics of α1‐
adrenoceptor subtypes in the bovine prostate using the radioligand binding assay …

Two district alpha (1)-adrenoceptor subtypes in the human prostate: assessment by radioligand binding assay using 3H-prazosin.

K Maruyama, J Fukutomi, T Chiba… - General …, 1996 - europepmc.org
1. We showed that there were two distinct alpha (1)-adrenoceptor subtypes (alpha (1H) and
alpha (IL)) in the human prostate which show different affinities for 3H-prazosin. 2. WB4101 …

Identification of α1-adrenoceptor subtypes in the dog prostate

T Ohmura, S Sakamoto, H Hayashi, S Kigoshi… - Urological …, 1993 - Springer
The α 1-adrenoceptor subtypes of dog prostate were characterized in binding and functional
experiments. In saturation experiments,[3 H] prazosin bound to α 1-adrenoceptors with high …

Alpha1-adrenoceptors in human prostate: characterization and binding characteristics of alpha1-antagonists

S Yamada, C Tanaka, R Kimura, K Kawabe - Life sciences, 1994 - Elsevier
The role of alpha 1-adrenoceptors in the mediation of autonomic functions, particularly in the
control of the cardiovascular system, is widely known. It has been shown that alpha 1 …

Functional identification of α1-adrenoceptor subtypes in human prostate: comparison with those in rat vas deferens and spleen

CM Teng, JH Guh, FN Ko - European journal of pharmacology, 1994 - Elsevier
The effects of some α 1-adrenoceptor antagonists (prazosin, nonselective for the α 1A-and α
1B-adrenoceptor subtypes; 5-methyl-urapidil, selective for the α 1A-adrenoceptor subtype …

Alpha1 adrenoceptor subtypes in the human prostate

H Lepor, R Tang, S Meretyk, E Shapiro - The Journal of urology, 1993 - Elsevier
High affinity α 1 adrenoceptors have been characterized in the human prostate. The tension
of prostatic smooth muscle is mediated by the α 1 adrenoceptor. The present study …