Background: In 2013, the Declaration of Helsinki mandated that every research study
involving human subjects must have its protocol registered in a publicly accessible database …

Background In 2013, the Declaration of Helsinki changed to mandate that all research
studies involving human subjects, rather than just clinical trials alone, must have a protocol …

BACKGROUND: Evidence-based medicine has had a profound impact on healthcare. In the
field of Plastic surgery, powerful examples include; less radical skin cancer excision margins …

Background Ensuring that published studies are of the highest methodological quality is a
critical step in plastic surgery's transition to a more evidence-based field. Reporting …

Background: Recent studies have identified a high incidence of discrepancy between
registered and published outcomes in registered medical and surgical randomized …

Introduction The Declaration of Helsinki 2013 encourages the registration of all research
studies involving human participants. However, emphasis has been placed on prospective …

Background In 2013, the Declaration of Helsinki was updated and required the registration
of all research studies involving human participants. Prior registries focussed on the …

Abstract Background The Declaration of Helsinki has called for the registration of all
research studies involving human participants. Despite this, prior registries did not allow …

Background: Reproducible research—defined as the ability to replicate a study with its
published materials and procedures—is integral to ensuring the validity of published studies …

Background Trial registration and the reporting of trial results are essential to increase
transparency in clinical research. Although both have been strongly promoted in recent …