Prolactin-secreting adenomas (prolactinomas) are the most prevalent form of pituitary
tumors in humans. Our knowledge of the formation of these tumors is limited. Experimental …

Prolactin-secreting adenomas (prolactinomas) are the most prevalent form of pituitary
tumors in humans, and increased tumor growth under estrogenic influence in female …

Prolactinoma is the most common type of primary pituitary tumors. It occurs more frequently
in women than in men. Dopaminergic agonists are effective in the shrinkage of prolactin …

Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in
tumor size, behavior and incidence have been described. These differences have been …

Dysregulation of the signaling pathways that govern lactotrope biology contributes to
tumorigenesis of prolactin (PRL)-secreting adenomas, or prolactinomas, leading to a state of …

Progesterone (P4) has controversial physiological effects on the regulation of the lactotroph
population. While some studies have shown a negative role for P4 in prolactin secretion and …

Introduction 3. Physiology of pituitary prolactin 3.1. Physiology of pituitary prolactin 3.2.
Prolcatinomas in humans and animals 3.3. Estrogen actions on prolactinomas 3.4. Alcohol …

Dopamine and estradiol interact in the regulation of lactotroph cell proliferation and prolactin
secretion. Ablation of the dopamine D2 receptor gene (Drd2−/−) in mice leads to a sexually …

In recent years the demonstration that human pituitary adenomas are monoclonal in origin
provides further evidence that pituitary neoplasia arise from the replication of a single …

Prolactin-secreting tumors (prolactinomas) represent the most common pituitary tumor type,
accounting for 47–66% of functional pituitary tumors. Prolactinomas are usually benign and …