Purpose Mutations in the zona pellucida glycoprotein genes have been reported to be
associated with empty follicle syndrome (EFS) and abnormal zona pellucida (ZP). In this …

Purpose The aim of this study was to identify the disease-causing mutations found in three
infertile female patients who were diagnosed with abnormal zona pellucida (ZP) and empty …

Research question Which genetic variants might explain the causes of empty follicle
syndrome (EFS) and abnormal zona pellucida (ZP) and affect the success of treatment with …

ZP1 is a critical glycoprotein in the formation of the zona pellucida. It plays an indispensable
role in the maturation of oocytes. To identify the causative gene of empty follicle syndrome …

Purpose Empty follicle syndrome (EFS) refers to the inability to obtain mature oocytes after
appropriate ovarian stimulation during the process of in vitro fertilization (IVF). However, the …

Purpose To identify a pathogenic gene mutation in a female infertility proband characterized
by empty follicle syndrome (EFS) and explore the genetic cause of EFS. Methods Whole …

Purpose To identify disease-causing genes involved in female infertility. Methods Whole-
exome sequencing and Sanger DNA sequencing were used to identify the mutations in …

Objective To identify the major causative gene (s) of genuine empty follicle syndrome
(GEFS) characterized by oocyte degeneration. Design Genetic and functional studies …

Empty follicle syndrome (EFS) is defined as the failure to aspirate oocytes from mature
ovarian follicles during in vitro fertilization. Except for some cases caused by …

Purpose Empty follicle syndrome (EFS) is a complex reproductive disorder characterized by
the repeated failure to aspirate oocytes from mature ovarian follicles during in vitro …