quality of life (6-minute walk test and the Minnesota Living with Heart Failure Questionnaire
score, respectively) and reduced scar tissue and left-ventricular sphericity index, markers of …

Cardiac cell therapies offer distinct and exciting advantages over current treatments to
prevent postinfarction heart failure because they can reverse ventricular remodeling and …

Myocardial infarction results in loss of cardiomyocytes, scar formation, ventricular
remodelling, and eventually heart failure. In recent years, cell therapy has emerged as a …

Degeneration of cardiac tissues is considered a major cause of mortality in the western
world and is expected to be a greater problem in the forthcoming decades. Cardiac damage …

Rationale: Allogeneic cardiac stem cells (AlloCSC-01) have shown protective,
immunoregulatory, and regenerative properties with a robust safety profile in large animal …

Cardiac cell therapy has now been in clinical use since 10years. Both autologous skeletal
myoblasts and bone marrow-derived different cell subsets (mononuclear cells …

Stem cell therapy is one of the most promising therapeutic innovations to help restore
cardiac structure and function after ischemic insults to the heart. However, phase I and II …

Despite improvements in emergency treatment, myocardial infarction is often the beginning
of a downward spiral leading to congestive heart failure. Other than heart transplantation …

Not long ago, it was assumed that mammalian hearts were so differentiated that
regeneration of cardiac tissue was not possible, but now an increasing amount of …

Introduction Stem cell therapy has emerged as a promising strategy for the treatment of
ischemic cardiomyopathy. Sources of data Multiple candidate cell types have been used in …