Vascular diseases leading to thrombo-occlusion are the leading cause of morbidity and
mortality worldwide. Revascularization and restoration of antegrade blood flow is critical for …

Streptokinase is one of the most commonly used thrombolytic agents for the treatment of
thromboembolism. Short half-life of the streptokinase requires administration of higher dose …

In recent times, search for potent and highly selective thrombolytic agents with minimal side
effects has become a major area of research. The aim of the present study was to develop …

Protease encapsulation and its targeted release in thrombi may contribute to the reduction of
haemorrhagic complications of thrombolysis. We aimed to prepare sterically stabilized …

It remains a major challenge to develop a selective and effective fibrinolytic system for
thrombolysis with minimal undesirable side effects. Herein, we report a multifunctional …

Several plasminogen activators (PAs) have been found effective in treating different
thromboembolic diseases. However, administration of conventional thrombolytic therapy is …

Development of tools for direct thrombus imaging represents a key step for diagnosis and
treatment of stroke. Nanoliposomal carriers of contrast agents and thrombolytics can be …

The present study was aimed to study the effect of RGD peptide conjugation on the bio-
distribution behaviour of long circulatory liposomes in the thrombosed rat model. Further …

Streptokinase is an efficient thrombolytic agent used to treat thromboembolic disorders.
Conventional streptokinase formulations have limited thrombolytic activity and several …

Delivery systems for therapeutic angiogenesis that deliver angiogenic factors to ischemic
tissues have recently been fabricated. However, these systems are designed for surgical …