Enhancing the function of PLGA-collagen scaffold by incorporating TGF-β1-loaded PLGA-PEG-PLGA nanoparticles for cartilage tissue engineering using human …

P Ghandforoushan, J Hanaee, Z Aghazadeh… - Drug Delivery and …, 2022 - Springer
Since cartilage has a limited capacity for self-regeneration, treating cartilage degenerative
disorders is a long-standing difficulty in orthopedic medicine. Researchers have scrutinized …

Novel nanocomposite scaffold based on gelatin/PLGA-PEG-PLGA hydrogels embedded with TGF-β1 for chondrogenic differentiation of human dental pulp stem cells …

P Ghandforoushan, J Hanaee, Z Aghazadeh… - International Journal of …, 2022 - Elsevier
In the current study, a novel nanocomposite hydrogel scaffold comprising of natural-based
gelatin and synthetic-based (poly D, L (lactide-co-glycolide)-b-poly (ethylene glycol)-b-poly …

Dual growth factor delivery using PLGA nanoparticles in silk fibroin/PEGDMA hydrogels for articular cartilage tissue engineering

M Fathi‐Achachelouei, D Keskin, E Bat… - … Research Part B …, 2020 - Wiley Online Library
Degeneration of articular cartilage due to damages, diseases, or age‐related factors can
significantly decrease the mobility of the patients. Various tissue engineering approaches …

Cartilage regeneration using mesenchymal stem cells and a PLGA–gelatin/chondroitin/hyaluronate hybrid scaffold

H Fan, Y Hu, C Zhang, X Li, R Lv, L Qin, R Zhu - Biomaterials, 2006 - Elsevier
The study was to produce a novel hybrid poly-(lactic-co-glycolic acid)(PLGA)–
gelatin/chondroitin/hyaluronate (PLGA–GCH) scaffold and evaluate its potentials in cartilage …

A pilot study of conically graded chitosan–gelatin hydrogel/PLGA scaffold with dual‐delivery of TGF‐β1 and BMP‐2 for regeneration of cartilage–bone interface

F Han, F Zhou, X Yang, J Zhao… - Journal of Biomedical …, 2015 - Wiley Online Library
Repair of cartilage–bone interface tissue remains challenging, because it combines different
cell types and gradients of composition and properties. To enable simultaneous …

Nanohybrid biodegradable scaffolds for TGF-β3 release for the chondrogenic differentiation of human mesenchymal stem cells

M Qasim, NXT Le, TPT Nguyen, DS Chae… - International Journal of …, 2020 - Elsevier
An ideal scaffold for bone tissue engineering should have chondroinductive, biodegradable,
and biocompatible properties, as well as the ability to absorb and slowly release the …

Hydrophilic gelatin and hyaluronic acid-treated PLGA scaffolds for cartilage tissue engineering

NJ Chang, YR Jhung, CK Yao… - Journal of Applied …, 2013 - journals.sagepub.com
Tissue engineering provides a new strategy for repairing damaged cartilage. Surface and
mechanical properties of scaffolds play important roles in inducing cell growth. Aim The aim …

TGF‐β3 immobilized PLGA‐gelatin/chondroitin sulfate/hyaluronic acid hybrid scaffold for cartilage regeneration

H Fan, H Tao, Y Wu, Y Hu, Y Yan… - Journal of biomedical …, 2010 - Wiley Online Library
Although most in vitro studies indicate that transforming growth factor β3 (TGF‐β3)
immobilized scaffold is suitable for cartilage tissue engineering, in vivo studies of implanting …

Fabrication of poly(lactide‐co‐glycolide) scaffold filled with fibrin gel, mesenchymal stem cells, and poly(ethylene oxide)‐b‐poly(L‐lysine)/TGF‐β1 plasmid DNA complexes for …

B Li, J Yang, L Ma, F Li, Z Tu… - Journal of Biomedical …, 2013 - Wiley Online Library
A poly (lactide‐co‐glycolide)(PLGA) scaffold filled with fibrin gel, mesenchymal stem cells
(MSCs) and poly (ethylene oxide)‐b‐poly (l‐lysine)(PEO‐b‐PLL)/pDNA‐TGF‐β1 complexes …

Rat cartilage repair using nanophase PLGA/HA composite and mesenchymal stem cells

H Li, Q Zheng, Y Xiao, J Feng… - Journal of Bioactive …, 2009 - journals.sagepub.com
Biodegradable polymer/bioceramic composite poly (lactide-coglycolide)/hydroxyapatite
(PLGA/HA) was studied for bone tissue engineering. The PLGA/HA composite was …