Dengue vaccines approach the finish line

R Edelman - Clinical Infectious Diseases, 2007 - academic.oup.com
The spread of dengue virus (DV) via its Aedes mosquito vector throughout most of the
tropics has led to a worldwide resurgence of epidemic dengue, including dengue …

Prospects for a dengue virus vaccine

SS Whitehead, JE Blaney, AP Durbin… - Nature Reviews …, 2007 - nature.com
The number of cases of severe dengue disease continues to grow in endemic areas of
southeast Asia, Central and South America, and other subtropical regions. Children bear the …

[HTML][HTML] The dengue vaccine pipeline: Implications for the future of dengue control

LM Schwartz, ME Halloran, AP Durbin, IM Longini Jr - Vaccine, 2015 - Elsevier
Dengue has become the most rapidly expanding mosquito-borne infectious disease on the
planet, surpassing malaria and infecting at least 390 million people per year. There is no …

Dengue vaccines: recent developments, ongoing challenges and current candidates

MA McArthur, MB Sztein, R Edelman - Expert review of vaccines, 2013 - Taylor & Francis
Dengue is among the most prevalent and important arbovirus diseases of humans. To
effectively control this rapidly spreading disease, control of the vector mosquito and a safe …

Vaccines for the prevention of dengue: development update

SJ Thomas, TP Endy - Human vaccines, 2011 - Taylor & Francis
The dengue viruses (DENV) are mosquito-borne flaviviruses which cause a spectrum of
clinical disease known as “dengue,” and have emerged and re-emerged as a significant …

Dengue vaccines: implications for dengue control

ML Robinson, AP Durbin - Current opinion in infectious diseases, 2017 - journals.lww.com
The efficacy and safety profile of the recently approved dengue vaccine is favorable only in
previously dengue exposed recipients, which limits its potential for global control. Future …

Dengue vaccine: priorities and progress

MG Guzman, M Muné, G Kourí - Expert Review of Anti-Infective …, 2004 - Taylor & Francis
Dengue transmission has increased considerably in the past 20 years. Currently, it can only
be reduced by mosquito control; however, the application of vector-control methods are …

The necessity and quandaries of dengue vaccine development

SJ Thomas - Journal of Infectious Diseases, 2011 - academic.oup.com
Dengue is an emerging and reemerging arboviral disease of great global public health
importance. Increased transmission and disease outbreaks are being driven by population …

Dengue vaccine development: challenges and prospects

A Wilder-Smith - Current Opinion in Infectious Diseases, 2022 - journals.lww.com
Although dengue-primed individuals can already benefit from vaccination with the first
licensed dengue vaccine CYD-TDV, the public health need for the dengue-naive population …

Dengue vaccine: the need, the challenges, and progress

AL Rothman, FA Ennis - The Journal of infectious diseases, 2016 - academic.oup.com
With regard to scientific progress on dengue, it could be said that we are living in the best of
times and the worst of times. As recently as the 1980s, dengue was considered among the …