The aim of the present study was to examine the multi‑targeted potential of a monoclonal
antibody against mucin‑1 (MUC1) and novel octahydropyrazin [2, 1‑a: 5, 4‑a'] diisoquinoline …

Background: The aim of the study was to examine the molecular mechanism of the
anticancer action of a monoclonal antibody against MUC1 and a diisoquinoline derivative …

Breast cancer is the most common malignant cancer in women. Triple-negative breast
cancer (TNBC) has a poorer prognosis than other subtypes and is challenging to treat …

Abstract Objective Overexpression of METCAM/MUC18, an immunoglobulin-like cell-
adhesion molecule, promotes tumorigenesis and progression of human breast cancer cells …

Mucin1 (MUC1) is aberrantly glycosylated and overexpressed in various cancers, and it
plays a crucial role in cancerogenesis. MUC1 is a type I membranous protein composed of α …

The present study aimed to investigate the binding of circulating mucin 1 (MUC1) antibody
with serum MUC1 antigen in stage IV breast cancer. Serum samples of 61 patients with …

Abstract Mucin 1 (MUC1) is a high molecular weight transmembrane glycoprotein, that is
overexpressed in> 90% of breast cancers. It serves a crucial role in anti‑apoptosis and tumor …

Introduction One of the most pressing concerns associated with breast cancer-targeted
therapies is resistance to Tamoxifen and Herceptin. Such drug resistance is usually …

Introduction MUC1 is a cell-surface glycoprotein that establishes a molecular barrier at the
epithelial surface and engages in morphogenetic signal transduction. Alterations in MUC1 …

The anti-carcinogenic effect of the new quinazolinone compound, named MMD, was tested
on MCF-7 human breast cancer cell line. The synthesis of quinazolinone-based compounds …