Comparative genomics, using the model organism approach, has provided powerful insights
into the structure and evolution of whole genomes. Unfortunately, only a small fraction of …

The rapid accumulation of complete genomic sequences offers the opportunity to carry out
an analysis of inter-and intra-individual genome variation within a species on a routine …

Due to advances in sequencing technologies, large-scale genomic research has become
feasible for many biologists who study organisms that are not traditionally used as model …

Whether for basic research or biotechnology, DNA microarrays have become indispensable
tools for studying the transcriptome. Normally, analyses begin with a set of known cDNA …

At the heart of genomics lies the precise determination of an organism's DNA sequence.
Palacios-Flores et al. present a simple, sensitive, precise, and essentially non-statistical …

Comparative analysis is one of the most powerful methods available for understanding the
diverse and complex systems found in biology, but it is often limited by a lack of …

We present a de novo assembly of a eukaryote transcriptome using 454 pyrosequencing
data. The Glanville fritillary butterfly (Melitaea cinxia; Lepidoptera: Nymphalidae) is a …

We have developed a universal web server application (KARMA) that allows comparison
and annotation of user-defined pairs of microarray platforms based on diverse types of …

Here we present the successful application of the microarray technology platform to the
analysis of DNA polymorphisms. Using the rice genome as a model, we demonstrate the …

Background Intra-species genetic variation can be used to investigate population structure,
selection, and gene flow in non-model vertebrates; and due to the plummeting costs for …