T2-weighted μMRI and Evoked Potential of the Visual System Measurements During the Development of Hypomyelinated Transgenic Mice

M Martin, SD Reyes, TD Hiltner, MI Givogri… - Neurochemical …, 2007 - Springer
Our objective was to follow the course of a dysmyelinating disease followed by partial
recovery in transgenic mice using non-invasive high-resolution (117× 117× 70 μm) magnetic …

Proton magnetic resonance in myelin deficient brains of mutant mice

FA Jolesz, DA Kirschner, P Jakab… - Journal of the neurological …, 1989 - Elsevier
The role of myelin in determining the magnetic resonance (MR) characterization of the
central nervous system (CNS) was investigated in unmyelinated brains of normal fetal mice …

Region-specific myelin pathology in mice lacking the golli products of the myelin basic protein gene

EC Jacobs, TM Pribyl, K Kampf… - Journal of …, 2005 - Soc Neuroscience
The myelin basic protein (MBP) gene encodes two families of proteins, the classic MBP
constituents of myelin and the golli-MBPs, the function of which is less well understood. In …

T2 relaxation time as a marker of brain myelination: experimental MR study in two neonatal animal models

E Miot-Noirault, L Barantin, S Akoka… - Journal of neuroscience …, 1997 - Elsevier
The progress of myelination in the brain was evaluated by visualization of grey/white matter
differentiation on magnetic resonance (MR) images and quantitative analysis of MR data. In …

On the occurrence of hypomyelination in a transgenic mouse model: a consequence of the myelin basic protein promoter?

S Gaupp, J Arezzo, DJ Dutta, GR John… - … of Neuropathology & …, 2011 - academic.oup.com
Central nervous system hypomyelination is a feature common to anumber of transgenic (Tg)
mouse lines that express a variety of unrelated exogenous (ie non–central nervous system) …

Abnormal upregulation of myelin genes underlies the critical period of myelination in undernourished developing rat brain

JE Royland, G Konat, RC Wiggins - Brain research, 1993 - Elsevier
Since myelin gene expression is suppressed during active myelination of the
undernourished brain, this study was designed to determine the effects of undernourishment …

[HTML][HTML] Dose response and time course of manganese-enhanced magnetic resonance imaging for visual pathway tracing in vivo

W Wang, H Xu, Y Li, Z Ma, X Sun… - Neural Regeneration …, 2016 - journals.lww.com
Axonal tracing is useful for detecting optic nerve injury and regeneration, but many
commonly used methods cannot be used to observe axoplasmic flow and synaptic …

Myelin basic protein deposition in the optic and sciatic nerves of dysmyelinating mutants quaking, jimpy, Trembler, mld, and shiverer during development

C Jacque, A Delassalle, M Raoul… - Journal of …, 1983 - Wiley Online Library
An ontogenetic survey of the basic protein of myelin, common to both central and peripheral
nervous systems, was carried out on normal C57B1 and five dysmyelinating mutant mice …

Targeted overexpression of a golli-myelin basic protein isoform to oligodendrocytes results in aberrant oligodendrocyte maturation and myelination

EC Jacobs, SD Reyes, CW Campagnoni… - ASN …, 2009 - journals.sagepub.com
Recently, several in vitro studies have shown that the golli-myelin basic proteins regulate
Ca2+ homoeostasis in OPCs (oligodendrocyte precursor cells) and immature OLs …

Myelin acquisition in the central nervous system of the mouse revealed by an MBP-Lac Z transgene

DR Foran, AC Peterson - Journal of Neuroscience, 1992 - Soc Neuroscience
Myelin has pronounced effects upon the morphology, function, and growth of axons in the
mammalian CNS. Consequently, oligodendrocyte development and myelination have been …