Background: Although the pentavalent rotavirus vaccine was highly efficacious against
rotavirus diarrhea in clinical trials, the effectiveness of vaccine under field conditions in the …

Background: A recent postlicensure study from El Salvador showed that the monovalent
rotavirus vaccine conferred 76% protection against rotavirus hospitalizations. We further …

Nicaragua was the first developing nation to implement universal infant rotavirus
immunization with the pentavalent rotavirus vaccine (RV5). Initial studies of vaccine …

Background: Nicaragua was the first developing nation to implement routine immunization
with the pentavalent rotavirus vaccine (RV5). In this RV5-immunized population …

Background: Single-strain rotavirus vaccine was added to the national immunization
program in Mexico in May 2007. We assessed the impact of vaccination on the number of …

OBJECTIVE: To evaluate the duration of protection of pentavaent rotavirus vaccine (RV5)
against rotavirus hospitalizations in Nicaragua, a developing country in Central America …

Background Rotaviruses are the principal known etiologic agents of severe diarrhea among
infants and young children worldwide. Although a rhesus rotavirus–based quadrivalent …

BACKGROUND: In October 2006, a rotavirus vaccine was introduced in Nicaragua for
routine immunization of all children. We document the baseline diarrheal disease burden in …

We estimated the incidence of watery diarrhea in the community before and after
introduction of the pentavalent rotavirus vaccine in León, Nicaragua. A random sample of …

Background: In December 2000, a large outbreak of gastroenteritis occurred in El Salvador
that was associated with hospitalizations and deaths among children nationwide. Public …