Plants from Suriname (South-America) and several Annona species, including A. muricata,
A. ckerimolia, A. montana and A. glabra were screened for 5-HT1A receptor binding activity …

Ligand-binding-studies on twelve different receptors were used for screening extracts from
plants from Suriname (South-America). The results on 5-HT1A, A1 and NMDA receptors …

A 70% ethanol extract of California poppy (Eschscholzia californica) was able to bind to 5-
HT1A and 5-HT7 receptors at 100 μg/mL. The subsequent isolation procedure yielded the …

The fruit and the leaves of Annona muricata (Annonaceae) are used in traditional medicine
for their tranquillizing and sedative properties. Extracts of the plant have been shown to …

Background We recently focused on alkaloids in Uncaria hook (a constituent of the Kampo
medicine, yokukansan) and identified the pharmacological action of geissoschizine methyl …

In this investigation, 185 plant samples representing more than 30 plant families collected
from the Malaysian forests were assessed for their ability to inhibit specific radioligand …

The hot water and 70% ethanol extracts of dried mad-dog skullcap (Scutellaria lateriflora)
both bound to the 5-HT7 receptor, with 87.2±6.2% and 56.7±1.3% inhibition of [3H]-LSD …

ETHNOPHARMACOLOGICAL RELEVANCE: Yokukansan (YKS) is a traditional Japanese
medicine consisted of seven medicinal herbs and has been used for treatment of neurosis …

The traditional Japanese phytomedicine rikkunshito is traditionally used for the treatment of
gastrointestinal motility disorders, cachexia and nausea. These effects indicate 5-HT3 …

Serotonin receptor (5-HT7) binding assay-directed fractionation of a methanol extract of the
dried roots of Angelica sinensis led to the isolation and identification of 21 compounds …