Male sex remains an independent risk factor for respiratory distress syndrome (RDS) in
preterm infants. Insufficient Na+ transport-mediated alveolar fluid clearance contributes to …

Preterm infants frequently suffer from respiratory distress syndrome (RDS), possibly due to
lower expression of epithelial Na+ channels (ENaC). RDS incidence is sex-specific …

Respiratory distress syndrome (RDS) is the most frequent pulmonary complication in
preterm infants. RDS incidence differs between genders, which has been called the male …

Alveolar fluid clearance mediates perinatal lung transition to air breathing in newborn
infants, which is accomplished by epithelial Na+ channels (ENaC) and Na-K-ATPase. Male …

Background: The airway epithelial sodium channel (ENaC) is rate limiting for postnatal
alveolar fluid clearance. Increased lung water content is a feature of respiratory distress …

Within this review, sex-specific differences in alveolar epithelial functions are discussed with
special focus on preterm infants and the respiratory disorders associated with premature …

Purpose Glucocorticoids and progesterone exert stimulatory effects on epithelial Na+
transport, including increased mRNA expression of the participating ion transporters …

Background: Respiratory distress due to inadequate lung liquid clearance is a significant
problem in infants delivered late preterm or early term, especially by elective cesarean …

At birth, lung fluid clearance is coupled to Na+ transport through epithelial Na+ channels
(ENaC) in the distal lung epithelium. We evaluated the effect of postnatal glucocorticoids …

Keratinocyte growth factor (KGF) caused cystic dilation of mouse fetal lung explants in vitro,
markedly increasing the luminal volume of lung buds and disrupting branching …