Alzheimer disease is the most common neurodegenerative disorder and cause of senile
dementia. It is characterized by an accelerated memory loss, and alterations of mood …

Alzheimer's disease is a neurodegenerative disorder associated with age which represents
the most common cause of dementia. It is characterized by an accelerated memory loss …

Animal models of Alzheimer's disease (AD) can be used to determine the progressive
neurodegeneration characteristics of AD in vivo using magnetic resonance imaging (MRI) …

Transgenic mice are a valuable tool in the investigation of neurodegenerative disorders
such as Alzheimer's disease. The triple transgenic mouse (3× Tg-AD) is a model of …

Transgenic animal models of Alzheimer's disease (AD) are widely used to investigate
mechanisms of pathophysiology and cognitive dysfunctions. A model with a very early …

Which behavioral test is the most sensitive for detecting cognitive deficits in the 3xTg-AD at
6.5 months of age? The 3xTg-AD mouse model of Alzheimer's disease (AD) has three …

Alzheimer's disease (AD) is characterized by distinct behavioral and cognitive deficits that
differ from those observed in normal aging. Transgenic models of AD are a promising tool in …

The triple transgenic Alzheimer's disease (3xTg-AD) strain is a common mouse model used
for studying the pathology and mechanism of Alzheimer's disease (AD). The 3xTg-AD strain …

One hundred years ago, the German psychiatrist and neuropathologist Alois Alzheimer gave
a lecture in which he identified a disease of the cerebral cortex [1] that would ultimately bear …

The 3xTg-AD mouse model of Alzheimer's disease (AD) has both amyloid beta plaque and
tau tangle pathology. However, the results of behavioural testing with these mice have been …