Coxiella burnetii is an obligate intracellular bacterial pathogen that causes the zoonosis Q
fever. While an effective whole-cell vaccine (WCV) against Q fever exists, the vaccine has …

Q fever is caused by the intracellular bacterium Coxiella burnetii, for which there is no
approved vaccine in the United States. A formalin-inactivated whole-cell vaccine (WCV) from …

Coxiella burnetii is an obligate intracellular bacterium which, in humans, causes the disease
Q fever. Although Q fever is most often a mild, self-limiting respiratory disease, it can cause a …

Designation as a Category B biothreat agent has propelled Coxiella burnetii from a relatively
obscure, underappreciated,“niche” microorganism on the periphery of bacteriology, to one of …

Background The obligate intracellular bacterial pathogen Coxiella burnetii causes the
zoonosis Q fever. The intracellular niche of C. burnetii has led to the assumption that cell …

Coxiella burnetii is an obligate intracellular bacterium that causes a worldwide zoonotic
disease, Q fever. Since C. burnetii infection is an occupational hazard and could develop …

ABSTRACT Q fever is a zoonotic disease caused by infection with the bacterium Coxiella
burnetii. Infection with C. burnetii results in humoral and cellular immune responses, both of …

Coxiella burnetii is a Gram-negative obligate intracellular pathogen and the causative agent
of Q fever in humans. Q fever causes acute flu-like symptoms and may develop into a …

Coxiella burnetii is the etiological agent of Q fever, a disease that is often spread to humans
via inhalational exposure to the bacteria from contaminated agricultural sources. Outbreaks …

To elucidate the mechanisms of vaccine-induced protective immunity against Coxiella
burnetii infection, we compared the protective efficacy and immunogenicity between formalin …