Effect of co-administration of the selective 5-HT1A receptor antagonist WAY 100,635 and selective 5-HT1B/1D receptor antagonist GR 127,935 on anxiolytic effect of …
I Muraki, T Inoue, T Koyama - European journal of pharmacology, 2008 - Elsevier
This study investigated the effect of co-administration of the selective 5-HT1A receptor
antagonist WAY 100,635 and selective 5-HT1B/1D receptor antagonist GR 127,935 with a …
antagonist WAY 100,635 and selective 5-HT1B/1D receptor antagonist GR 127,935 with a …
5‐HT depletion, but not 5‐HT1A antagonist, prevents the anxiolytic‐like effect of citalopram in rat contextual conditioned fear stress model
T Masuda, H Nishikawa, T Inoue, H Toda… - Acta …, 2013 - cambridge.org
ObjectiveSelective serotonin reuptake inhibitors (SSRIs) have been widely used in the
treatment of most anxiety disorders. In this study, to clarify the mechanism of the anxiolytic …
treatment of most anxiety disorders. In this study, to clarify the mechanism of the anxiolytic …
Effects of the co-administration of 5-HT1A receptor antagonists with an SSRI in conditioned fear stress-induced freezing behavior
S Hashimoto, T Inoue, T Koyama - Pharmacology Biochemistry and …, 1997 - Elsevier
The effects of the co-administration of the serotonin (5-HT) 1A receptor antagonists NAN-190
or (+)-WAY100135 with a selective 5-HT reuptake inhibitor (SSRI) citalopram on conditioned …
or (+)-WAY100135 with a selective 5-HT reuptake inhibitor (SSRI) citalopram on conditioned …
Effects of acute citalopram on the expression of conditioned freezing in naive versus chronic citalopram-treated rats
S Hashimoto, T Inoue, I Muraki, T Koyama - Progress in Neuro …, 2009 - Elsevier
An acute challenge with selective serotonin (5-HT) reuptake inhibitors (SSRIs) reduces the
conditioned freezing in rats, a model of anxiety. The increase in the 5-HT levels in the nerve …
conditioned freezing in rats, a model of anxiety. The increase in the 5-HT levels in the nerve …
Effect of subchronic lithium carbonate treatment on anxiolytic-like effect of citalopram and MKC-242 in conditioned fear stress in the rat
I Muraki, T Inoue, S Hashimoto, T Izumi, K Ito… - European journal of …, 1999 - Elsevier
We investigated the effect of citalopram [selective serotonin (5-HT) reuptake inhibitor] and
MKC-242 (5-[3-{(2S)-(1, 4-Benzodioxan-2-ylmethyl) amino} propoxy]-1, 3-benzo-dioxol …
MKC-242 (5-[3-{(2S)-(1, 4-Benzodioxan-2-ylmethyl) amino} propoxy]-1, 3-benzo-dioxol …
A Complex Impact of Systemically Administered 5-HT2A Receptor Ligands on Conditioned Fear
SM Hagsäter, R Pettersson, C Pettersson… - International Journal …, 2021 - academic.oup.com
Background Though drugs binding to serotonergic 5-HT2A receptors have long been
claimed to influence human anxiety, it remains unclear if this receptor subtype is best …
claimed to influence human anxiety, it remains unclear if this receptor subtype is best …
Synergistic effects of tandospirone and selective serotonin reuptake inhibitors on the contextual conditioned fear stress response in rats
H Nishikawa, T Inoue, T Izumi, T Koyama - European …, 2007 - Elsevier
The purpose of this study was to investigate the effects of co-administration of tandospirone
(a 5-HT1A receptor agonist) and individual selective serotonin reuptake inhibitors (SSRIs) …
(a 5-HT1A receptor agonist) and individual selective serotonin reuptake inhibitors (SSRIs) …
Involvement of 5-HT1A and 5-HT1B receptors for citalopram-induced hypothermia in the rat
S Oerther, S Ahlenius - Psychopharmacology, 2001 - Springer
Objectives: To examine the role of 5-HT 1A and 5-HT 1B receptors for citalopram-induced
hypothermia in the rat. Methods: Core temperature measurements were performed in adult …
hypothermia in the rat. Methods: Core temperature measurements were performed in adult …
Effect of citalopram, a selective serotonin reuptake inhibitor, on the acquisition of conditioned freezing
T Inoue, S Hashimoto, K Tsuchiya, T Izumi… - European journal of …, 1996 - Elsevier
The present study examined the effects of the selective serotonin (5-hydroxytryptamine, 5-
HT) reuptake inhibitor citalopram on the acquisition of conditioned freezing, an index of …
HT) reuptake inhibitor citalopram on the acquisition of conditioned freezing, an index of …
Selective serotonin reuptake inhibitor reduces conditioned fear through its effect in the amygdala
T Inoue, XB Li, T Abekawa, Y Kitaichi, T Izumi… - European journal of …, 2004 - Elsevier
Selective serotonin reuptake inhibitors are first-line treatment for most anxiety disorders, but
their mechanism of anxiolytic action has not been clarified. Selective serotonin reuptake …
their mechanism of anxiolytic action has not been clarified. Selective serotonin reuptake …