Liver failure after extended hepatectomy represents a major challenge in the surgery of
hepatic colorectal metastasis. A previous study has indicated that inhibition of …

Major hepatectomy or small‐for‐size liver transplantation may result in postoperative liver
failure. So far, no treatment is available to improve liver regeneration. Herein, we studied …

A rat model of liver metastases generated by intraportal injection of syngeneic tumor cells
after two-thirds hepatectomy to determine the optimal benefit of doxorubicin and/or cilostazol …

Background Hepatic arterial infusion (HAI) of specific anti-tumor drugs can be more effective
compared with systemic drug application. Herein, we studied whether HAI of temsirolimus is …

Nearly 50% of colorectal cancer (CRC) patients develop liver metastases with liver resection
being the only option to cure patients. Residual micrometastases or circulating tumor cells …

Metastasis of cancer cells is initiated by the cellular migration into extracellular matrix and
surrounding vessels. We previously showed that elevation of cAMP levels in cancer cells …

We have previously reported that colorectal cancer (CRC) liver metastases from patients,
who had received the selective cyclooxygenase 2 (COX-2) inhibitor rofecoxib (Vioxx) 25 mg …

Purpose: This study was to investigate the effect of capecitabine on recurrent tumor and
metastasis after curative resection of liver cancer, xenograft of a highly metastatic human …

Background Chemotherapy before resection of colorectal metastases in the liver is
extensively used and has been shown to induce histopathological changes in the liver …

Background. Arachidonic acid metabolites known to affect platelet function also interfere
with tumor growth and metastases. The purpose of this study was to evaluate the anti …