Both ionically and enzymatically crosslinkable alginate–tyramine conjugate as materials for cell encapsulation

S Sakai, K Kawakami - … of Biomedical Materials Research Part A …, 2008 - Wiley Online Library
The swelling behavior of the structural material of cell‐enclosing capsules is a key factor for
the successful transplantation of these capsules in the treatment of diseases. The present …

Chemistry and biocompatibility of alginate‐PLL capsules for immunoprotection of mammalian cells

P de Vos, CG Hoogmoed… - Journal of Biomedical …, 2002 - Wiley Online Library
Transplantation of encapsulated living cells is a promising approach for the treatment of a
wide variety of diseases. Large‐scale application of the technique, however, is hampered by …

Biocompatibility and surface structure of chemically modified immunoisolating alginate‐PLL capsules

CM Bünger, C Gerlach, T Freier… - … Research Part A: An …, 2003 - Wiley Online Library
Grafting of encapsulated living cells has the potential to cure a wide variety of diseases.
Large‐scale application of the technique, however, is hampered by insufficient …

Microcapsules made by enzymatically tailored alginate

BL Strand, YA Mørch, KR Syvertsen… - … Research Part A: An …, 2003 - Wiley Online Library
Alginate is widely used for encapsulation of cells. Alginate is a linear block copolymer
consisting of mannuronic acid (M) and guluronic acid (G). It has been shown that enzymes …

Biological properties of photocrosslinked alginate microcapsules

F Shen, AA Li, RM Cornelius, P Cirone… - … Research Part B …, 2005 - Wiley Online Library
An alternative form of gene therapy using recombinant cell lines delivering therapeutic
products encapsulated in alginate hydrogel has proven effective in treating many murine …

Biocompatibility and in vivo evaluation of oligochitosans as cationic modifiers of alginate/Ca microcapsules

M De Castro, G Orive, RM Hernández… - … Research Part A: An …, 2009 - Wiley Online Library
The present article investigates the substitution of poly‐l‐lysine by two different
oligochitosans as membrane‐coating capsule, and its effect on different functionality …

New capsule with tailored properties for the encapsulation of living cells

I Lacik, M Briššová, AV Anilkumar… - … Research: An Official …, 1998 - Wiley Online Library
A new capsule for the encapsulation and transplantation of pancreatic islets has been
developed. Five active ingredients are involved in the capsule formation process: high …

Improving covalent cell encapsulation with temporarily reactive polyelectrolytes

CM Gardner, MA Potter, HDH Stöver - Journal of materials science …, 2012 - Springer
Calcium alginate/poly-l-lysine beads were coated with either 50% hydrolyzed poly (methyl
vinyl ether–alt–maleic anhydride)(PMM 50), or with poly (vinyl dimethyl azlactone-co …

Encapsulation of various recombinant mammalian cell types in different alginate microcapsules

M Peirone, CJD Ross, G Hortelano… - … Research: An Official …, 1998 - Wiley Online Library
Microencapsulation of recombinant “universal” cells with immunoprotective membranes is
an alternate approach to somatic gene therapy. Therapeutic gene products secreted by …

Improvement of the biocompatibility of alginate/poly‐L‐lysine/alginate microcapsules by the use of epimerized alginate as a coating

A King, B Strand, AM Rokstad… - … Research Part A: An …, 2003 - Wiley Online Library
Abstract Alginate/poly‐l‐lysine (PLL)/alginate capsules are used widely for the
microencapsulation of cells. Alginate consists of guluronic acid and mannuronic acid, the …