[HTML][HTML] The effects of cholesterol oxidation on erythrocyte plasma membranes: a monolayer study

BD Lechner, P Smith, B McGill, S Marshall, JL Trick… - Membranes, 2022 - mdpi.com
Cholesterol plays a key role in the molecular and mesoscopic organisation of lipid
membranes and it is expected that changes in its molecular structure (eg, through …

[HTML][HTML] Cholesterol in phospholipid bilayers: positions and orientations inside membranes with different unsaturation degrees

I Ermilova, AP Lyubartsev - Soft Matter, 2019 - pubs.rsc.org
Cholesterol is an essential component of all animal cell membranes and plays an important
role in maintaining the membrane structure and physical–chemical properties necessary for …

Cholesterol under oxidative stress—How lipid membranes sense oxidation as cholesterol is being replaced by oxysterols

W Kulig, A Olżyńska, P Jurkiewicz, AM Kantola… - Free radical biology and …, 2015 - Elsevier
The behavior of oxysterols in phospholipid membranes and their effects on membrane
properties were investigated by means of dynamic light scattering, fluorescence …

[HTML][HTML] Lipoprotein-induced increases in cholesterol and 7-ketocholesterol result in opposite molecular-scale biophysical effects on membrane structure

MAA Ayee, I Levitan - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Under hypercholesterolemic conditions, exposure of cells to lipoproteins results in a subtle
membrane increase in the levels of cholesterol and 7-ketocholesterol, as compared to …

[PDF][PDF] Oxidation of cholesterol changes the permeability of lipid membranes

WT Kulig, H Mikkolainen, A Olzynska, P Jurkiewicz… - Biophysical journal, 2017 - cell.com
The function of living systems is inherently based on cells, which are the key building blocks
of living organisms. Each cell in a human body is surrounded by a cell membrane, which …

[HTML][HTML] 25-hydroxycholesterol effect on membrane structure and mechanical properties

MM Domingues, B Gomes, A Hollmann… - International Journal of …, 2021 - mdpi.com
Cholesterol is responsible for the plasticity of plasma membranes and is involved in
physiological and pathophysiological responses. Cholesterol homeostasis is regulated by …

Differential effects of cholesterol on acyl chain order in erythrocyte membranes as a function of depth from the surface. An electron paramagnetic resonance (EPR) …

MB Cassera, AM Silber, AM Gennaro - Biophysical chemistry, 2002 - Elsevier
The purpose of this work is to analyze the effects of cholesterol modulation on acyl chain
ordering in the membrane of human erythrocytes as a function of depth from the surface …

[HTML][HTML] Molecular simulations of the effects of phospholipid and cholesterol peroxidation on lipid membrane properties

AJP Neto, RM Cordeiro - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Non-enzymatic lipid peroxidation may change biomembrane structure and function. Here,
we employed molecular dynamics simulations to study the effects of either phospholipid or …

Interactions between ether phospholipids and cholesterol as determined by scattering and molecular dynamics simulations

J Pan, X Cheng, FA Heberle, B Mostofian… - The Journal of …, 2012 - ACS Publications
Cholesterol and ether lipids are ubiquitous in mammalian cell membranes, and their
interactions are crucial in ether lipid mediated cholesterol trafficking. We report on …

[PDF][PDF] Oxidation of polyunsaturated phospholipid decreases the cholesterol content at which cholesterol bilayer domains start to form in phospholipid-cholesterol …

L Mainali, M Zareba, WK Subczynski - Biophysical Journal, 2017 - cell.com
Saturation-recovery electron paramagnetic resonance and differential scanning calorimetry
were used to determine the cholesterol content at which pure cholesterol bilayer domains …